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Recombinant Mouse CD47 Protein

Recombinant Mouse CD47 Protein

级别和纯度:

≥95%(SDS-PAGE)

表达系统: HEK293
Accession #: NP_034711
蛋白标签: C-His
生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Mouse SIRP alpha /CD172a Fc Chimera is coated at 2 μg/mL, Recombinant Mouse CD47 binds with an apparent Kd <0.6 nM. Also measured by its ability to antagonize mouse red blood cell adhesion to immobilized Recombinant Mouse SIRP alpha /CD172a Fc Chimera. The ED50 for this effect is 2.0-8.0 μg/mL. Optimal dilutions should be determined by each laboratory for each application.
内毒素水平: <0.1 EU/μg

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货号 (SKU)	包装规格	是否现货
rp167416-10μg	10μg	现货
rp167416-50μg	50μg	现货
rp167416-100μg	100μg	现货
rp167416-1mg	1mg	期货

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点击查看蛋白信息: CD47

Accession#: NP_034711 (1) Accession#: Q61735 (5) Cd47 (19) Gene ID: 16423 (5)

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基本描述

产品名称	Recombinant Mouse CD47 Protein
别名	整合素关联蛋白(IAP)重组蛋白
英文别名	antigen identified by monoclonal 1D8 \| Antigenic surface determinant protein OA3 \| CD47 antigen (Rh-related antigen, integrin-associated signal transducer) \| CD47 antigen \| CD47 glycoprotein \| CD47 molecule \| CD47 \| IAP \| IAPintegrin associated protein \|
规格或纯度	ActiBioPure™, High performance, 无动物源, 生物活性, Carrier Free, ≥95%(SDS-PAGE)
产品介绍	Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
生物活性	Measured by its binding ability in a functional ELISA. When Recombinant Mouse SIRP alpha /CD172a Fc Chimera is coated at 2 μg/mL, Recombinant Mouse CD47 binds with an apparent Kd <0.6 nM. Also measured by its ability to antagonize mouse red blood cell adhesion to immobilized Recombinant Mouse SIRP alpha /CD172a Fc Chimera. The ED50 for this effect is 2.0-8.0 μg/mL. Optimal dilutions should be determined by each laboratory for each application.
内毒素水平	<0.1 EU/μg
表达系统	HEK293
种属	小鼠(Mouse)
氨基酸	19-158 aa
序列	QLLFSNVNSIEFTSCNETVVIPCIVRNVEAQSTEEMFVKWKLNKSYIFIYDGNKNSTTTDQNFTSAKISVSDLINGIASLKMDKRDAMVGNYTCEVTELSREGKTVIELKNRTAFNTDQGSACSYEEEKGGCKLVSWFSPHHHHHH
蛋白标签	C-His
无载体	Yes
无动物源	Yes
Accession #	NP_034711
来源	重组表达
预测分子量	16.51 kDa
SDS-PAGE	30 - 45 kDa, under reducing conditions; 30 - 45 & 60 - 90 kDa, under non-reducing conditions.

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶	Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型	蛋白质

图片

SDS-PAGE: Recombinant Mouse CD47 Protein (rp167416)

Recombinant Mouse CD47 Protein (rp167416) - SDS-PAGE
2 μg/lane of Recombinant Mouse CD47 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 30 - 45 kDa under reducing conditions and 30 - 45 & 60 - 90 kDa under non-reducing conditions.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ25F0217780	分析证书	rp167416
ZJ25F0217779	分析证书	rp167416
ZJ25F0217778	分析证书	rp167416

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