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血液瘤CAR靶点
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Recombinant Human CD33 Protein种属: 人(Human) Accession #: P20138表达系统: HEK293 蛋白标签: C-hFc & His 内毒素水平: <0.1 EU/μg生物活性: 1、Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is 1‑4 µg/mL. 2、Immobilized Recombinant Human CD33 Protein (rp143966) at 2.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859). The ED50 for this effect is 391.3 ng/mL.
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Recombinant Human CD22 Protein种属: 人(Human) Accession #: P20273表达系统: HEK293 蛋白标签: C-Fc & His 内毒素水平: <0.1 EU/μg生物活性: Immobilized Recombinant Human CD22 Protein (rp143882) at 1 μg/mL can bind Recombinant CD22 Antibody (Ab094265) with a EC50 is 4.6 ng/mL.
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Recombinant Human CD72 Protein种属: 人(Human) Accession #: P21854表达系统: HEK293 蛋白标签: C-hFc & His 内毒素水平: <0.1 EU/μg生物活性: Measured by the ability of the immobilized protein to induce IFN-gamma secretion in NK‑92 human natural killer lymphoma cells. The ED50 for this effect is 3-15 μg/mL.
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Recombinant Human CD4 Protein种属: 人(Human) Accession #: P01730表达系统: HEK293 蛋白标签: C-His 内毒素水平: <1.0 EU/μg生物活性: Measured by the ability of the immobilized protein to support the adhesion of HeLa human cervical epithelial carcinoma cells. The ED50 for this effect is 40.0 ng/mL. Measured by its binding ability in a functional ELISA. Immobilized Human CD4 protein (rp175911) at 1.0 μg/mL can bind Ibalizumab (anti-CD4) (Ab170728) with the EC50 of 52.66 ng/mL.
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Recombinant Mouse PD-L1/B7-H1 Protein种属: 小鼠(Mouse) Accession #: Q9EP73表达系统: HEK293 蛋白标签: C-His 内毒素水平: <0.1 EU/μg生物活性: Immobilized Recombinant Mouse PD-L1/B7-H1 Protein (rp154493) at 10 μg/mL can bind Recombinant Mouse PD-1 Protein (rp149974), the EC₅₀ of this effect is 3.07 μg/mL.
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Recombinant Bovine CD4 Protein种属: 牛(Bovine) Accession #: F1MJK4表达系统: HEK293 蛋白标签: C-His 内毒素水平: <1.0 EU/μg生物活性: Measured by the ability of the immobilized protein to support the adhesion of NIH‑3T3 mouse embryonic fibroblast cells.The ED50for this effect is 0.1-0.5 μg/mL after a 1 hour incubation at37 °C.Optimal dilutions should be determined by each laboratory for each application.
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Recombinant Human Siglec-3/CD33 Protein种属: 人(Human) Accession #: P20138表达系统: HEK293 蛋白标签: C-His 内毒素水平: <1.0 EU/μg生物活性: 1. Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is < 6 µg/mL. 2. Immobilized Recombinant Human Siglec-3/CD33 Protein (rp169578) at 1.0 μg/mL can bind Vadastuximab (anti-CD33) (Ab182778) with the EC50 of 10.59 ng/mL. 3. Immobilized Recombinant Human Siglec-3/CD33 Protein (rp169578) at 1.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859) with the EC50 of 36.93 ng/mL.
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