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Recombinant CD41a Antibody (AF405)

Recombinant CD41a Antibody (AF405)

COA

级别和纯度:

已验证

ExactAb™

5 μL/test

应用:

Flow Cytometry

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG1
克隆号: P50A23
偶联: AF405

有货

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
Ab213115-10T	10T	现货
Ab213115-25T	25T	现货
Ab213115-100T	100T	现货

查看相关系列

点击查看靶蛋白信息: ITGA2B

Accession#:P08514 (25) AF405 (97) Gene ID:3674 (25) GP2B (20) ITGA2B (25) ITGAB (17)

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基本信息

产品名称	Recombinant CD41a Antibody (AF405)
别名	血小板膜糖蛋白Ⅱb（CD41）单克隆抗体 \| Anti-CD41a抗体 \| CD41a抗体 \| CD41a单抗
英文别名	CD41 antigen \| CD41 \| CD41BHPA3 \| GP2B \| GP2Bintegrin alpha-IIb \| GPalpha IIb \| GPIIb \| GTA \| HPA3 \| Integrin alpha 2b \| integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41) \| integrin, alpha 2b (platelet glycoprotein IIb of IIb
规格或纯度	ExactAb™, 已验证, 5 μL/test
生化机理	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed:9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity).
宿主种属	小鼠(Mouse)
特异性	Human CD41a
种属反应性	人(Human)
免疫原	Purified platelet membrane glycoproteins
阳性对照	Flow Cytometry: Human peripheral blood platelets
偶联	AF405
Excitation(nm)	Violet Laser(405nm)
Emission(nm)	422nm
Ex/Em(nm)	Ex:401nm;Em:422nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

ITGA2B Tclin 整合素α-IIb(Integrin alpha-IIb) (0 活性数据)

点击查看靶蛋白信息： ITGA2B

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD41a Antibody (AF405) (Ab213115)

Recombinant CD41a Antibody (AF405) (Ab213115) - Flow Cytometry
Flow cytometry analysis of CD41a expression by human peripheral blood platelets (red) compared to an isotype control (blue). Cells were stained with Recombinant CD41a Antibody (AF405) (Ab213115) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (AF405) (Ab190076). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	5μl/test For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.