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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab191665-10μg |
10μg |
现货 ![]() |
| |
| Ab191665-25μg |
25μg |
现货 ![]() |
| |
| Ab191665-100μg |
100μg |
现货 ![]() |
|
| 产品名称 | CD45R Rat mAb (AF700) |
|---|---|
| 别名 | 蛋白酪氨酸磷酸酶受体C(CD45)抗体 | CD45R抗体 | AF700 标记Anti-CD45R抗体[RA3-6B2] | 蛋白酪氨酸磷酸酶受体C(CD45)抗体 | CD45R抗体 | AF700 标记Anti-CD45R抗体[RA3-6B2] | CD45R 大鼠单克隆抗体 (AF700) | CD45R 大鼠单抗 (AF700) |
| 英文别名 | LCA | CD45 | T200 | GP180 | IMD105 | B220 | CD45 antigen | CD45R | EC 3.1.3.48 | L-CA | LY5 | protein tyrosine phosphatase, receptor type, C | receptor-type tyrosine-protein phosphatase C | T200 glycoprotein | T200 leukocyte common antigen | T200receptor |
| 规格或纯度 | ExactAb™, 已验证, Ex:696nm, Em:719nm, 0.5 mg/mL |
| 生化机理 | 通过抗原受体激活 T 细胞所需的蛋白酪氨酸蛋白磷酸酶。与 DPP4 结合后,可作为 T 细胞共激活的正向调节因子。第一个 PTPase 结构域具有酶活性,而第二个 PTPase 结构域似乎会影响第一个 PTPase 结构域的底物特异性。T 细胞活化后,该蛋白可招募 SKAP1 和 FYN 并使其去磷酸化。 |
| 宿主种属 | 大鼠(Rat) |
| 特异性 | CD45R |
| 种属反应性 | 人(Human),小鼠(Mouse) |
| 免疫原 | Abelson murine leukemia virus-induced pre-B tumor cells |
| 阳性对照 | Flow: C57BL/6 mouse splenocytes. |
| 偶联 | AF700 |
| Excitation(nm) | Red Laser(633nm) |
| Emission(nm) | 719nm |
| Ex/Em(nm) | Ex:696nm;Em:719nm |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | RA3-6B2 |
| Format | Whole IgG |
| 亚型 | Rat IgG2a |
| 轻链亚型 | kappa |
| SDS-PAGE | 26.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 207.1 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 储存缓冲液 | Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300. |
| 防腐剂 | 0.05% Proclin300 |
| 浓度 | 0.5 mg/mL |
| 储存温度 | 2-8°C储存,避光,禁止冷冻 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | 未稀释的抗体溶液应保存在 2°C 至 8°C 之间,避免长时间暴露在光线下。切勿冷冻。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
CD45R Rat mAb (AF700) (Ab191665) - Flow Cytometry
Flow cytometry analysis of CD45R expression by C57BL/6 mouse splenocytes (right panel) compared to an isotype control (left panel). Cells were stained with CD45R Rat mAb (AF700) (Ab191665) at 0.1μg/test for 1 hour at 4°C. Left panel - Rat IgG (AF700) (Ab190242).
CD45R Rat mAb (AF700) (Ab191665) - Flow Cytometry
Flow cytometry analysis of CD45R expression by C57BL/6 mouse splenocytes (red) compared to an isotype control (blue). Cells were stained with CD45R Rat mAb (AF700) (Ab191665) at 0.1μg/test for 1 hour at 4°C. Blue - Rat IgG (AF700) (Ab190242). Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry |
≤0.3 μg/test,
the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume
|
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab191665 | |
| 分析证书 | Ab191665 | |
| 分析证书 | Ab191665 |
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