基本信息

产品名称	Garivulimab (anti-PD-L1)
别名	加利福单抗(抗 PD-L1)
英文别名	B7 H antibody \| B7 H1 antibody \| B7 homolog 1 antibody \| B7-H1 antibody \| B7H antibody \| B7H1 antibody \| CD 274 antibody \| CD-274 antibody \| CD274 antibody \| CD274 antigen antibody \| CD274 molecule antibody \| MGC142294 antibody \| MGC142296 antibody \| OTTH
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	CD274
种属反应性	人(Human),小鼠(Mouse),食蟹猴(Cynomolgus monkey)
偶联	Unconjugated
作用类型	抑制剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	144.3 kDa
纯化方法	Protein A purified
纯度	>95% (SDS-PAGE&SEC)
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	2342597-81-1
分子类型	抗体

关联靶点（人）

CD274 Tclin 程序性细胞死亡 1 配体 1(Programmed cell death 1 ligand 1) (0 活性数据)

点击查看靶蛋白信息： CD274

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Garivulimab (anti-PD-L1) (Ab182922)

Garivulimab (anti-PD-L1) (Ab182922) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-L1 (red) with Garivulimab (anti-PD-L1) (Ab182922) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Garivulimab (anti-PD-L1) (Ab182922)

Garivulimab (anti-PD-L1) (Ab182922) - ELISA
Immobilized Recombinant Human PD-L1 protein (rp199666) at 1.0 μg/mL can bind Garivulimab (anti-PD-L1) (Ab182922) with the EC50 of 69.29 ng/mL.