Recombinant MUC2 Antibody

COA

级别和纯度:

重组

已验证

ExactAb™

0.4 mg/mL

应用:

宿主种属: 兔(Rabbit)
种属反应性: 人(Human), 大鼠(Rat)
亚型: Rabbit IgG
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab116430-10μl	10μl	期货
Ab116430-50μl	50μL	期货
Ab116430-100μl	100μL	期货
Ab116430-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: MUC2

Accession#:Q02817 (2) Gene ID:4583 (2) MUC2 (2)

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基本信息

产品名称	Recombinant MUC2 Antibody
别名	黏蛋白2重组兔单克隆抗体 \| 上皮膜抗原2重组兔单克隆抗体 \| 重组 MUC2 抗体
英文别名	Intestinal mucin 2 antibody \| Intestinal mucin-2 antibody \| MLP antibody \| MUC 2 antibody \| MUC-2 antibody \| Muc2 antibody \| MUC2_HUMAN antibody \| Mucin 2 antibody \| Mucin 2 intestinal antibody \| Mucin 2 intestinal/tracheal antibody \| Mucin 2 oligomeric m
规格或纯度	ExactAb™, Validated, 重组, 0.4 mg/mL
宿主种属	兔(Rabbit)
特异性	MUC2
种属反应性	人(Human),大鼠(Rat)
免疫原	A synthetic peptide derived from human MUC2 (AA 5000-5100).
阳性对照	WB: SH-SY5Y lysates.
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Rabbit IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
防腐剂	0.02% Sodium azide
浓度	0.4 mg/mL
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

MUC2 Tdark 黏蛋白-2(Mucin-2) (0 活性数据)

点击查看靶蛋白信息： MUC2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

应用

应用名称	稀释比例
WB	1/500-1/1000

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

引用文献

1. Todd D Taylor,Hideki Noguchi,Yasushi Totoki,Atsushi Toyoda,Yoko Kuroki,Ken Dewar,Christine Lloyd,Takehiko Itoh,Tadayuki Takeda,Dae-Won Kim,Xinwei She,Karen F Barlow,Toby Bloom,Elspeth Bruford,Jean L Chang,Christina A Cuomo,Evan Eichler,Michael G FitzGerald,David B Jaffe,Kurt LaButti,Robert Nicol,Hong-Seog Park,Christopher Seaman,Carrie Sougnez,Xiaoping Yang,Andrew R Zimmer,Michael C Zody,Bruce W Birren,Chad Nusbaum,Asao Fujiyama,Masahira Hattori,Jane Rogers,Eric S Lander,Yoshiyuki Sakaki. (2006-03-24) Human chromosome 11 DNA sequence and analysis including novel gene identification.. Nature, 440 ((7083)): (497-500). [PMID:16554811]
2. Gum, J R JR and 5 more authors.. (1992) The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.. The Journal of biological chemistry, (25): [PMID:1400449]
3. Xu, G G and 8 more authors.. (1992) Human intestinal mucin-like protein (MLP) is homologous with rat MLP in the C-terminal region, and is encoded by a gene on chromosome 11 p 15.5.. Biochemical and biophysical research communications, (16): [PMID:1550588]
4. Toribara, N W NW and 6 more authors.. (1991) MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism.. The Journal of clinical investigation, [PMID:1885763]
5. Gum, J R JR and 5 more authors.. (1989) Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism.. The Journal of biological chemistry, (15): [PMID:2703501]
6. Gum, J R JR, Hicks, J W JW, Toribara, N W NW, Siddiki, B B and Kim, Y S YS.. (1994) Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.. The Journal of biological chemistry, (28): [PMID:8300571]
7. Silverman, H S HS and 10 more authors.. (2001) In vivo glycosylation of mucin tandem repeats.. Glycobiology, [PMID:11445551]
8. Lidell, Martin E ME, Johansson, Malin E V ME and Hansson, Gunnar C GC.. (2003) An autocatalytic cleavage in the C terminus of the human MUC2 mucin occurs at the low pH of the late secretory pathway.. The Journal of biological chemistry, (18): [PMID:12582180]
9. Ishinaga, Hajime H and 5 more authors.. (2005) Pranlukast inhibits NF-kappaB activation and MUC2 gene expression in cultured human epithelial cells.. Pharmacology, [PMID:15475658]
10. Moehle, Christoph C and 9 more authors.. (2006) Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease.. Journal of molecular medicine (Berlin, Germany), [PMID:17058067]
11. Park, Sung-Woo SW and 7 more authors.. (2009) The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.. Proceedings of the National Academy of Sciences of the United States of America, (28): [PMID:19359471]
12. Johansson, Malin E V ME, Thomsson, Kristina A KA and Hansson, Gunnar C GC.. (2009) Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.. Journal of proteome research, [PMID:19432394]
13. Javitt, Gabriel and 6 more authors.. (2019) Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains.. Journal of molecular biology, (6): [PMID:31310764]

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稀释计算器

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体积（添加到小瓶中）

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所需的复溶浓度

Recombinant MUC2 Antibody

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器