基本描述

别名	维生素 A 醛
英文别名	all-trans-Retinene \| Retinal, 9-cis- \| trans-Retinal \| all-E-Retinal \| Retinyl aldehyde \| tocopherol alpha- \| (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenal \| NCGC00258558-01 \| 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohe
规格或纯度	Moligand™, ≥98%
英文名称	all trans-Retinal
生化机理	全反式视黄醛在体内通过视黄醛脱氢酶的作用转化为视黄酸。视黄酸是视黄酸受体（RAR）和视黄醇 X 受体（RXR）的配体，这两种受体是调节正常细胞和恶性细胞生长和分化的转录因子。视黄醛异构体也是一种发色团，可与视蛋白（一种与 G 蛋白相连的跨膜蛋白家族）结合，在视觉和非视觉系统中形成光敏受体。全反式视黄醛是一种强效光敏剂。
应用	An oxidized form of retinol that is a corotenoid component of the visual pigments.All trans-Retinal has been used: · in optogenetic experiments · in electrophysiological experiment · to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium · in decidual transformation of human endometrial stromal cells
储存温度	-20°C储存
运输条件	超低温冰袋运输
作用类型	门控抑制剂
作用机制	CNGA2 的门控抑制剂
产品介绍	An oxidized form of retinol that is a corotenoid component of the visual pigments. Product Description： All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables. An oxidized form of retinol that is a corotenoid component of the visual pigments.
纯度	≥98%

关联靶点（人）

SNCA Tchem α-突触核蛋白(Alpha-synuclein) (1 活性数据)

点击查看靶蛋白信息： SNCA

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CNGA2 Tchem 环核苷酸门控嗅觉通道(Cyclic nucleotide-gated olfactory channel) (1 活性数据)

点击查看靶蛋白信息： CNGA2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

APP Tclin 淀粉样β蛋白A4(Amyloid-beta A4 protein) (1 活性数据)

点击查看靶蛋白信息： APP

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

ESR1 Tclin Estrogen receptor alpha (17718 活性数据)

点击查看靶蛋白信息： ESR1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)

点击查看靶蛋白信息： NR3C1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 活性数据)

点击查看靶蛋白信息： PPARG

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 活性数据)

点击查看靶蛋白信息： KCNH2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

AKR1B1 Tclin Aldose reductase (1404 活性数据)

点击查看靶蛋白信息： AKR1B1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 活性数据)

点击查看靶蛋白信息： RXRA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CXCL8 Tchem Interleukin-8 (642 活性数据)

点击查看靶蛋白信息： CXCL8

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

APP Tclin Amyloid-beta A4 protein (8510 活性数据)

点击查看靶蛋白信息： APP

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)

点击查看靶蛋白信息： ALDH1A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NR1H4 Tclin Bile acid receptor FXR (6228 活性数据)

点击查看靶蛋白信息： NR1H4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 活性数据)

点击查看靶蛋白信息： ALOX15

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 活性数据)

点击查看靶蛋白信息： TP53

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

AKR1B10 Tchem Aldo-keto reductase family 1 member B10 (300 活性数据)

点击查看靶蛋白信息： AKR1B10

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SNCA Tchem Alpha-synuclein (10960 活性数据)

点击查看靶蛋白信息： SNCA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)

点击查看靶蛋白信息： TDP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

OPN1LW Tbio Long-wave-sensitive opsin 1 (8 活性数据)

点击查看靶蛋白信息： OPN1LW

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NR2E1 Tbio Nuclear receptor subfamily 2 group E member 1 (116 活性数据)

点击查看靶蛋白信息： NR2E1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

lef Anthrax lethal factor (7585 活性数据)

点击查看靶蛋白信息： lef

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 活性数据)

点击查看靶蛋白信息： rep

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)

点击查看靶蛋白信息： Nfe2l2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 活性数据)

点击查看靶蛋白信息： Rorc

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 活性数据)

点击查看靶蛋白信息： Nr1i2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

EC号	204-135-8
分子类型	小分子
IIUPAC Name	(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenal
INCHI	1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChi Key	NCYCYZXNIZJOKI-OVSJKPMPSA-N
Smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=O)C)C
Isomeric SMILES	CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C
分子量	284.44
Reaxy-Rn	2055098
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2055098&ln=

化学和物理性质

溶解性	Soluble in Clear Yellow Solution at 5mg/ml Acetonitrile.
敏感性	对光线敏感
熔点	62-64 °C
分子量	284.400 g/mol
XLogP3	6.200
氢键供体数Hydrogen Bond Donor Count	0
氢键受体数Hydrogen Bond Acceptor Count	1
可旋转键计数Rotatable Bond Count	5
精确质量Exact Mass	284.214 Da
单同位素质量Monoisotopic Mass	284.214 Da
拓扑极表面积Topological Polar Surface Area	17.100 Å²
重原子数Heavy Atom Count	21
形式电荷Formal Charge	0
复杂度Complexity	522.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	4
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	4
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07, GHS08
信号词	危险
危险声明	H302: 吞食有害 H315: 引起皮肤刺激 H360: 可能损害生育力或未出生的孩子 H413: 可能对水生生物造成长期的有害影响
预防措施声明	P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P302+P352: 如皮肤沾染：用水充分清洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前，获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P318: 如果暴露或担心，请就医。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany	3

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到18个结果

批号(Lot Number)	证书类型	货号
G2511113	分析证书	A122355
G2511114	分析证书	A122355
G2511115	分析证书	A122355
D2307462	分析证书	A122355
D2307463	分析证书	A122355
D2307467	分析证书	A122355
I2406092	分析证书	A122355
I2406093	分析证书	A122355
I2406094	分析证书	A122355
I2406095	分析证书	A122355
E2508007	分析证书	A122355
G2222182	分析证书	A122355
I2110066	分析证书	A122355
B2314220	分析证书	A122355
D2307465	分析证书	A122355
G2222087	分析证书	A122355
G2222181	分析证书	A122355
G2003178	分析证书	A122355

显示更多⌵

可替换产品

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Janet R Sparrow,Yalin Wu,Chul Y Kim,Jilin Zhou. (2009-08-12) Phospholipid meets all-trans-retinal: the making of RPE bisretinoids.. Journal of lipid research, 51 ((2)): (247-261). [PMID:19666736]
2. Sajjida Jaffer,Vasily Vorobyov,Frank Sengpiel. (2012-08-14) Effects of different forms of monocular deprivation on primary visual cortex maps.. Visual neuroscience, 29 ((4-5)): (247-253). [PMID:22882840]
3. Song-Qi Gao,Tadao Maeda,Kiichiro Okano,Krzysztof Palczewski. (2012-08-25) A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids.. Investigative ophthalmology & visual science, 53 ((10)): (6314-6323). [PMID:22918645]
4. Takefumi Morizumi,Keita Sato,Yoshinori Shichida. (2012-11-28) Spectroscopic analysis of the effect of chloride on the active intermediates of the primate L group cone visual pigment.. Biochemistry, 51 ((50)): (10017-10023). [PMID:23176664]
5. Thomas P Sakmar. (2012-12-12) Biochemistry. Redder than red.. Science (New York, N.Y.), 338 ((6112)): (1299-1300). [PMID:23224543]
6. Lei Zhang,Fenghua Wang,Yuan Jiang,Shan Xu,Fengqing Lu,Wenqiu Wang,Xiangjun Sun,Xiaodong Sun. (2013-01-02) Migration of retinal pigment epithelial cells is EGFR/PI3K/AKT dependent.. Frontiers in bioscience (Scholar edition), 5 (661-671). [PMID:23277077]
7. Elena Smolensky Koganov,Amiram Hirshfeld,Mordechai Sheves. (2013-01-22) Retinal β-ionone ring-salinixanthin interactions in xanthorhodopsin: a study using artificial pigments.. Biochemistry, 52 ((7)): (1290-1301). [PMID:23331279]
8. Ming Zhong,Riki Kawaguchi,Miki Kassai,Hui Sun. (2013-02-01) Retina, retinol, retinal and the natural history of vitamin A as a light sensor.. Nutrients, 4 ((12)): (2069-2096). [PMID:23363998]
9. Shiho Kawamura,Moritz Gerstung,Alejandro T Colozo,Jonne Helenius,Akiko Maeda,Niko Beerenwinkel,Paul S-H Park,Daniel J Müller. (2013-02-26) Kinetic, energetic, and mechanical differences between dark-state rhodopsin and opsin.. Structure (London, England : 1993), 21 ((3)): (426-437). [PMID:23434406]
10. Mitsumasa Koyanagi,Eiichiro Takada,Takashi Nagata,Hisao Tsukamoto,Akihisa Terakita. (2013-03-13) Homologs of vertebrate Opn3 potentially serve as a light sensor in nonphotoreceptive tissue.. Proceedings of the National Academy of Sciences of the United States of America, 110 ((13)): (4998-5003). [PMID:23479626]
11. Roberto Rodríguez-Ortiz,M Carmen Limón,Javier Avalos. (2013-04-02) Functional analysis of the carS gene of Fusarium fujikuroi.. Molecular genetics and genomics : MGG, 288 ((3-4)): (157-173). [PMID:23543145]
12. Hideo Kohno,Yu Chen,Brian M Kevany,Eric Pearlman,Masaru Miyagi,Tadao Maeda,Krzysztof Palczewski,Akiko Maeda. (2013-04-11) Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.. The Journal of biological chemistry, 288 ((21)): (15326-15341). [PMID:23572532]
13. Keiichi Inoue,Takashi Tsukamoto,Yuki Sudo. (2013-06-05) Molecular and evolutionary aspects of microbial sensory rhodopsins.. Biochimica et biophysica acta, 1837 ((5)): (562-577). [PMID:23732219]
14. Sridevi Mony,Seung Joon Lee,Jeffrey F Harper,Sonali P Barwe,Sigrid A Langhans. (2013-07-03) Regulation of Na,K-ATPase β1-subunit in TGF-β2-mediated epithelial-to-mesenchymal transition in human retinal pigmented epithelial cells.. Experimental eye research, 115 (113-122). [PMID:23810808]
15. Antoine Gautier. (2013-07-09) Structure determination of α-helical membrane proteins by solution-state NMR: emphasis on retinal proteins.. Biochimica et biophysica acta, 1837 ((5)): (578-588). [PMID:23831435]
16. Yasushi Imamoto,Yoshinori Shichida. (2013-09-12) Cone visual pigments.. Biochimica et biophysica acta, 1837 ((5)): (664-673). [PMID:24021171]
17. Tadao Maeda,Mee Jee Lee,Grazyna Palczewska,Stefania Marsili,Paul J Tesar,Krzysztof Palczewski,Masayo Takahashi,Akiko Maeda. (2013-10-17) Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo.. The Journal of biological chemistry, 288 ((48)): (34484-34493). [PMID:24129572]
18. Oznur Tastan,Arpana Dutta,Paula Booth,Judith Klein-Seetharaman. (2013-12-18) Retinal proteins as model systems for membrane protein folding.. Biochimica et biophysica acta, 1837 ((5)): (656-663). [PMID:24333783]
19. Tivadar Orban,Beata Jastrzebska,Krzysztof Palczewski. (2014-04-01) Structural approaches to understanding retinal proteins needed for vision.. Current opinion in cell biology, 27 (32-43). [PMID:24680428]
20. Nicholas C Flytzanis,Claire N Bedbrook,Hui Chiu,Martin K M Engqvist,Cheng Xiao,Ken Y Chan,Paul W Sternberg,Frances H Arnold,Viviana Gradinaru. (2014-09-16) Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons.. Nature communications, 5 (4894-4894). [PMID:25222271]
21. Ulrike Scheib,Katja Stehfest,Christine E Gee,Heinz G Körschen,Roman Fudim,Thomas G Oertner,Peter Hegemann. (2015-08-14) The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling.. Science signaling, 8 ((389)): (rs8-rs8). [PMID:26268609]
22. Minjuan Bian,Xiaoye Du,Jingang Cui,Peiwei Wang,Wenjian Wang,Weiliang Zhu,Teng Zhang,Yu Chen. (2016-02-28) Celastrol protects mouse retinas from bright light-induced degeneration through inhibition of oxidative stress and inflammation.. Journal of neuroinflammation, 13 (50-50). [PMID:26920853]
23. Elena G Govorunova,Oleg A Sineshchekov,Elsa M Rodarte,Roger Janz,Olivier Morelle,Michael Melkonian,Gane K-S Wong,John L Spudich. (2017-03-04) The Expanding Family of Natural Anion Channelrhodopsins Reveals Large Variations in Kinetics, Conductance, and Spectral Sensitivity.. Scientific reports, 7 (43358-43358). [PMID:28256618]
24. Daisuke Hattori,Yoshinori Aso,Kurtis J Swartz,Gerald M Rubin,L F Abbott,Richard Axel. (2017-05-16) Representations of Novelty and Familiarity in a Mushroom Body Compartment.. Cell, 169 ((5)): (956-969). [PMID:28502772]
25. James M Jeanne,Mehmet Fişek,Rachel I Wilson. (2018-06-19) The Organization of Projections from Olfactory Glomeruli onto Higher-Order Neurons.. Neuron, 98 ((6)): (1198-1213). [PMID:29909998]
26. Alexandria H Jaeger,Molly Stanley,Zachary F Weiss,Pierre-Yves Musso,Rachel Cw Chan,Han Zhang,Damian Feldman-Kiss,Michael D Gordon. (2018-10-12) A complex peripheral code for salt taste in Drosophila.. eLife, 7 [PMID:30307393]
27. Martyna J Grabowska,James Steeves,Julius Alpay,Matthew Van De Poll,Deniz Ertekin,Bruno van Swinderen. (2018-10-17) Innate visual preferences and behavioral flexibility in Drosophila.. The Journal of experimental biology, 221 ((Pt 23)): [PMID:30322983]
28. Jeffrey L Rhoades,Jessica C Nelson,Ijeoma Nwabudike,Stephanie K Yu,Ian G McLachlan,Gurrein K Madan,Eden Abebe,Joshua R Powers,Daniel A Colón-Ramos,Steven W Flavell. (2018-12-26) ASICs Mediate Food Responses in an Enteric Serotonergic Neuron that Controls Foraging Behaviors.. Cell, 176 ((1-2)): (85-97). [PMID:30580965]
29. Michael Telias,Bristol Denlinger,Zachary Helft,Casey Thornton,Billie Beckwith-Cohen,Richard H Kramer. (2019-03-17) Retinoic Acid Induces Hyperactivity, and Blocking Its Receptor Unmasks Light Responses and Augments Vision in Retinal Degeneration.. Neuron, 102 ((3)): (574-586). [PMID:30876849]
30. Christina E May,Anoumid Vaziri,Yong Qi Lin,Olga Grushko,Morteza Khabiri,Qiao-Ping Wang,Kristina J Holme,Scott D Pletcher,Peter L Freddolino,G Gregory Neely,Monica Dus. (2019-05-09) High Dietary Sugar Reshapes Sweet Taste to Promote Feeding Behavior in Drosophila melanogaster.. Cell reports, 27 ((6)): (1675-1685). [PMID:31067455]
31. Stephen X Zhang,Dragana Rogulja,Michael A Crickmore. (2019-09-03) Recurrent Circuitry Sustains Drosophila Courtship Drive While Priming Itself for Satiety.. Current biology : CB, 29 ((19)): (3216-3228). [PMID:31474539]
32. Lei Li,Haowen Liu,Qi Hall,Wei Wang,Yi Yu,Joshua M Kaplan,Zhitao Hu. (2019-09-12) A Hyperactive Form of unc-13 Enhances Ca2+ Sensitivity and Synaptic Vesicle Release Probability in C.\xa0elegans.. Cell reports, 28 ((11)): (2979-2995). [PMID:31509756]
33. Yu-Chieh David Chen,Scarlet Jinhong Park,Ryan Matthew Joseph,William W Ja,Anupama Arun Dahanukar. (2019-10-24) Combinatorial Pharyngeal Taste Coding for Feeding Avoidance in Adult Drosophila.. Cell reports, 29 ((4)): (961-973). [PMID:31644916]
34. Stephen C Thornquist,Kirill Langer,Stephen X Zhang,Dragana Rogulja,Michael A Crickmore. (2019-12-02) CaMKII Measures the Passage of Time to Coordinate Behavior and Motivational State.. Neuron, 105 ((2)): (334-345). [PMID:31786014]
35. Lifen Jiang,Yaxin Cheng,Shan Gao,Yincheng Zhong,Chengrui Ma,Tianyu Wang,Yan Zhu. (2020-01-22) Emergence of social cluster by collective pairwise encounters in Drosophila.. eLife, 9 [PMID:31959283]
36. Johnny Cruz-Corchado,Felicia K Ooi,Srijit Das,Veena Prahlad. (2020-01-31) Global Transcriptome Changes That Accompany Alterations in Serotonin Levels in Caenorhabditis elegans.. G3 (Bethesda, Md.), 10 ((4)): (1225-1246). [PMID:31996358]
37. Fei Wang,Kaiyu Wang,Nora Forknall,Christopher Patrick,Tansy Yang,Ruchi Parekh,Davi Bock,Barry J Dickson. (2020-02-28) Neural circuitry linking mating and egg laying in Drosophila females.. Nature, 579 ((7797)): (101-105). [PMID:32103180]
38. Renjie Wang,Qiaopeng Chen,Rongjing Zhang,Junhua Yuan. (2020-05-12) Measurement of the Internal Frictional Drag of the Bacterial Flagellar Motor by Fluctuation Analysis.. Biophysical journal, 118 ((11)): (2718-2725). [PMID:32392462]
39. Nils Otto,Markus W Pleijzier,Isabel C Morgan,Amelia J Edmondson-Stait,Konrad J Heinz,Ildiko Stark,Georgia Dempsey,Masayoshi Ito,Ishaan Kapoor,Joseph Hsu,Philipp M Schlegel,Alexander S Bates,Li Feng,Marta Costa,Kei Ito,Davi D Bock,Gerald M Rubin,Gregory S X E Jefferis,Scott Waddell. (2020-07-04) Input Connectivity Reveals Additional Heterogeneity of Dopaminergic Reinforcement in Drosophila.. Current biology : CB, 30 ((16)): (3200-3211). [PMID:32619479]
40. Nicolas Taveau,Aurélie Cubizolle,Laurent Guillou,Nicolas Pinquier,Espérance Moine,David Cia,Vasiliki Kalatzis,Joseph Vercauteren,Thierry Durand,Céline Crauste,Philippe Brabet. (2020-07-10) Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy.. Experimental & molecular medicine, 52 ((7)): (1090-1101). [PMID:32641711]
41. Cheng-Yi Chiang,Chia-Cheng Chou,Hsin-Yang Chang,Min-Feng Hsu,Po-Jung Pao,Ming-Hui Chiang,Andrew H-J Wang. (2020-08-01) Biochemical and molecular dynamics studies of archaeal polyisoprenyl pyrophosphate phosphatase from Saccharolobus solfataricus.. Enzyme and microbial technology, 139 (109585-109585). [PMID:32732034]
42. Cecilia Mezzera,Margarida Brotas,Miguel Gaspar,Hania J Pavlou,Stephen F Goodwin,Maria Luísa Vasconcelos. (2020-08-17) Ovipositor Extrusion Promotes the Transition from Courtship to Copulation and Signals Female Acceptance in Drosophila melanogaster.. Current biology : CB, 30 ((19)): (3736-3748). [PMID:32795437]
43. Govorunova, et al.. (2021) RubyACRs, nonalgal anion channelrhodopsins with highly red-shifted absorption.. Proceedings of the National Academy of Sciences of the USA, 117 (22833-22840). [PMID:32873643]
44. Sarita Hebbar,Kai Schuhmann,Andrej Shevchenko,Elisabeth Knust. (2020-10-14) Hydroxylated sphingolipid biosynthesis regulates photoreceptor apical domain morphogenesis.. The Journal of cell biology, 219 ((12)): [PMID:33048164]
45. Hu, et al.. (2021) A Neural Basis for Categorizing Sensory Stimuli to Enhance Decision Accuracy.. Current Biology, 30 (4896-4909). [PMID:33065003]
46. Jiang Bian,Zixu Wang,Yulan Dong,Jing Cao,Yaoxing Chen. (2020-10-30) Role of BMAL1 and CLOCK in regulating the secretion of melatonin in chick retina under monochromatic green light.. Chronobiology international, 37 ((12)): (1677-1692). [PMID:33115282]
47. Eric S Luth,Molly Hodul,Bethany J Rennich,Carmino Riccio,Julia Hofer,Kaitlin Markoja,Peter Juo. (2021-02-10) VER/VEGF receptors regulate AMPA receptor surface levels and glutamatergic behavior.. PLoS genetics, 17 ((2)): (e1009375-e1009375). [PMID:33561120]
48. X Huang. (2002-01-05) [Potentiation of arsenic trioxide-induced apoptosis by retinoic acid in retinoic acid sensitive and resistant HL-60 myeloid leukemia cells].. Chinese medical journal, 113 ((6)): (498-501). [PMID:11775865]
49. Eleonora S Imasheva,Sergei P Balashov,Jennifer M Wang,Elena Smolensky,Mordechai Sheves,Janos K Lanyi. (2008-04-11) Chromophore interaction in xanthorhodopsin--retinal dependence of salinixanthin binding.. Photochemistry and photobiology, 84 ((4)): (977-984). [PMID:18399915]
50. Tadao Maeda,Marcin Golczak,Akiko Maeda. (2012-03-21) Retinal photodamage mediated by all-trans-retinal.. Photochemistry and photobiology, 88 ((6)): (1309-1319). [PMID:22428905]
51. Basak Isin,Kalyan C Tirupula,Zoltán N Oltvai,Judith Klein-Seetharaman,Ivet Bahar. (2012-09-15) Identification of motions in membrane proteins by elastic network models and their experimental validation.. Methods in molecular biology (Clifton, N.J.), 914 (285-317). [PMID:22976035]
52. Yang Li,Yan Zhang,Rui Li,Wei Chen,Meredith Howell,Rui Zhang,Guoxun Chen. (2012-10-03) The hepatic Raldh1 expression is elevated in Zucker fatty rats and its over-expression introduced the retinal-induced Srebp-1c expression in INS-1 cells.. PloS one, 7 ((9)): (e45210-e45210). [PMID:23028851]
53. Eugenia Poliakov,Alexander N Gubin,Olivia Stearn,Yan Li,Maria Mercedes Campos,Susan Gentleman,Igor B Rogozin,T Michael Redmond. (2012-12-05) Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates.. PloS one, 7 ((11)): (e49975-e49975). [PMID:23209628]
54. Wenjing Wang,Zahra Nossoni,Tetyana Berbasova,Camille T Watson,Ipek Yapici,Kin Sing Stephen Lee,Chrysoula Vasileiou,James H Geiger,Babak Borhan. (2012-12-12) Tuning the electronic absorption of protein-embedded all-trans-retinal.. Science (New York, N.Y.), 338 ((6112)): (1340-1343). [PMID:23224553]
55. Tadao Maeda,Zhiqian Dong,Hui Jin,Osamu Sawada,Songqi Gao,Deepank Utkhede,Wendy Monk,Grazyna Palczewska,Krzysztof Palczewski. (2012-12-20) QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles.. Investigative ophthalmology & visual science, 54 ((1)): (455-466). [PMID:23249702]
56. Amir Wand,Itay Gdor,Jingyi Zhu,Mordechai Sheves,Sanford Ruhman. (2013-01-22) Shedding new light on retinal protein photochemistry.. Annual review of physical chemistry, 64 (437-458). [PMID:23331307]
57. Eglof Ritter,Patrick Piwowarski,Peter Hegemann,Franz J Bartl. (2013-02-27) Light-dark adaptation of channelrhodopsin C128T mutant.. The Journal of biological chemistry, 288 ((15)): (10451-10458). [PMID:23439646]
58. Zhao Zhao,Tao Sun,Yun Jiang,Lijiang Wu,Xiangzhong Cai,Xiaodong Sun,Xiangjun Sun. (2014-12-03) Photooxidative damage in retinal pigment epithelial cells via GRP78 and the protective role of grape skin polyphenols.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 74 (216-224). [PMID:25447759]
59. Soh Kohatsu,Daisuke Yamamoto. (2015-03-07) Visually induced initiation of Drosophila innate courtship-like following pursuit is mediated by central excitatory state.. Nature communications, 6 (6457-6457). [PMID:25743851]
60. Jannik N Pedersen,Jan S Pedersen,Daniel E Otzen. (2015-07-15) The Use of Liprotides To Stabilize and Transport Hydrophobic Molecules.. Biochemistry, 54 ((31)): (4815-4823). [PMID:26158206]
61. Diana M Wright,Deanna E Buenger,Timur M Abashev,Robert P Lindeman,Jixiang Ding,Lisa L Sandell. (2015-08-19) Retinoic acid regulates embryonic development of mammalian submandibular salivary glands.. Developmental biology, 407 ((1)): (57-67). [PMID:26278034]
62. Hai Li,Oleg A Sineshchekov,Gang Wu,John L Spudich. (2016-10-30) In Vitro Activity of a Purified Natural Anion Channelrhodopsin.. The Journal of biological chemistry, 291 ((49)): (25319-25325). [PMID:27789708]
63. Keiichi Inoue,Shota Ito,Yoshitaka Kato,Yurika Nomura,Mikihiro Shibata,Takayuki Uchihashi,Satoshi P Tsunoda,Hideki Kandori. (2016-11-18) A natural light-driven inward proton pump.. Nature communications, 7 (13415-13415). [PMID:27853152]
64. Chia-Yi Huang,Cheng-Chang Lien,Chau-Fu Cheng,Ting-Yun Yen,Chieh-Ju Chen,Meei-Ling Tsaur. (2017-03-23) K. The Journal of neuroscience : the official journal of the Society for Neuroscience, 37 ((17)): (4433-4449). [PMID:28320840]
65. Ying-Chou Chen,Fahim Farzadfard,Nava Gharaei,William C W Chen,Jicong Cao,Timothy K Lu. (2017-10-07) Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity.. Molecular cell, 68 ((1)): (247-257). [PMID:28985507]
66. Xuewu Sui,Erik R Farquhar,Hannah E Hill,Johannes von Lintig,Wuxian Shi,Philip D Kiser. (2018-06-28) Preparation and characterization of metal-substituted carotenoid cleavage oxygenases.. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 23 ((6)): (887-901). [PMID:29946976]
67. Ricardo Zacarias,Shigehiro Namiki,Gwyneth M Card,Maria Luisa Vasconcelos,Marta A Moita. (2018-09-14) Speed dependent descending control of freezing behavior in Drosophila melanogaster.. Nature communications, 9 ((1)): (3697-3697). [PMID:30209268]
68. Kristin M Scaplen,Nicholas J Mei,Hayley A Bounds,Sophia L Song,Reza Azanchi,Karla R Kaun. (2019-03-16) Automated real-time quantification of group locomotor activity in Drosophila melanogaster.. Scientific reports, 9 ((1)): (4427-4427). [PMID:30872709]
69. Ye Zhang,Tin Ki Tsang,Eric A Bushong,Li-An Chu,Ann-Shyn Chiang,Mark H Ellisman,Jürgen Reingruber,Chih-Ying Su. (2019-04-07) Asymmetric ephaptic inhibition between compartmentalized olfactory receptor neurons.. Nature communications, 10 ((1)): (1560-1560). [PMID:30952860]
70. Bixing Zhao,Yingchao Wang,Xionghong Tan,Xiaoyuan Zheng,Fei Wang,Kun Ke,Cuilin Zhang,Naishun Liao,Yuan Dang,Yingjun Shi,Youshi Zheng,Yunzhen Gao,Qin Li,Xiaolong Liu,Jingfeng Liu. (2019-05-01) An Optogenetic Controllable T Cell System for Hepatocellular Carcinoma Immunotherapy.. Theranostics, 9 ((7)): (1837-1850). [PMID:31037142]
71. Román A Corfas,Tarun Sharma,Michael H Dickinson. (2019-05-06) Diverse Food-Sensing Neurons Trigger Idiothetic Local Search in Drosophila.. Current biology : CB, 29 ((10)): (1660-1668). [PMID:31056390]
72. Lisha Shao,Phuong Chung,Allan Wong,Igor Siwanowicz,Clement F Kent,Xi Long,Ulrike Heberlein. (2019-05-11) A Neural Circuit Encoding the Experience of Copulation in Female Drosophila.. Neuron, 102 ((5)): (1025-1036). [PMID:31072787]
73. Nicholas M Tefft,Michaela A TerAvest. (2019-06-28) Reversing an Extracellular Electron Transfer Pathway for Electrode-Driven Acetoin Reduction.. ACS synthetic biology, 8 ((7)): (1590-1600). [PMID:31243980]
74. Marc C Liggins,Fengwu Li,Ling-Juan Zhang,Tatsuya Dokoshi,Richard L Gallo. (2019-08-20) Retinoids Enhance the Expression of Cathelicidin Antimicrobial Peptide during Reactive Dermal Adipogenesis.. Journal of immunology (Baltimore, Md. : 1950), 203 ((6)): (1589-1597). [PMID:31420464]
75. Ali El-Agamey,Thor B Melø,Maha A El-Hagrasy,Vassilia Partali,Shunichi Fukuzumi. (2020-09-28) Carotenoid radical ions: A laser flash photolysis study.. Journal of photochemistry and photobiology. B, Biology, 212 (112023-112023). [PMID:32980657]
76. Javier Valdes-Aleman,Richard D Fetter,Emily C Sales,Emily L Heckman,Lalanti Venkatasubramanian,Chris Q Doe,Matthias Landgraf,Albert Cardona,Marta Zlatic. (2020-10-30) Comparative Connectomics Reveals How Partner Identity, Location, and Activity Specify Synaptic Connectivity in Drosophila.. Neuron, 109 ((1)): (105-122). [PMID:33120017]
77. Tatsuya Ikuta,Wataru Shihoya,Masahiro Sugiura,Kazuho Yoshida,Masahito Watari,Takaya Tokano,Keitaro Yamashita,Kota Katayama,Satoshi P Tsunoda,Takayuki Uchihashi,Hideki Kandori,Osamu Nureki. (2020-11-07) Structural insights into the mechanism of rhodopsin phosphodiesterase.. Nature communications, 11 ((1)): (5605-5605). [PMID:33154353]
78. Yunchuan Zhang,Yinzhong Zhou,Xuchen Zhang,Lingling Wang,Yi Zhong. (2021-02-06) Clock neurons gate memory extinction in Drosophila.. Current biology : CB, 31 ((6)): (1337-1343). [PMID:33545046]
79. Rong Zhang, Wei Jia. (2022) Authenticity and traceability of goat milk: Molecular mechanism of β-carotene biotransformation and accessibility. FOOD CHEMISTRY, 388 (133073). [PMID:35483296] [10.1016/j.foodchem.2022.133073]
80. Zhipeng Qi, Xianyu Fan, Chunyi Zhu, Dongsheng Chang, Jianjun Pei, Linguo Zhao. (2021) Overexpression and Characterization of a Novel Plant Carotenoid Cleavage Dioxygenase 1 from Morus notabilis. CHEMISTRY & BIODIVERSITY, 19 (2): (e202100735). [PMID:34821468] [10.1002/cbdv.202100735]
81. Kaixuan Ke, Ling Guo, Zhipeng Qi, Dou Dou, Han Ma, Xianying Fang, Linguo Zhao. (2024) Molecular cloning, expression, and biochemical characterization of carotenoid cleavage dioxygenase 1 (LbCCD1) from Lycium barbarum. Molecular Catalysis, 569 (114561). [10.1016/j.mcat.2024.114561]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
A122355-50mg	50mg	现货
A122355-250mg	250mg	现货
A122355-1g	1g	现货
A122355-5g	5g	现货

全反式视黄醛, CNGA2 的门控抑制剂

库存信息

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

显示更多⌵

可替换产品

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器