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Tinurilimab (anti-CEACAM6) - Primary antibody, specific to CEACAM6, >95%, high purity, Human IgG2

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG2
  • Conjugation: Unconjugated
In stock
Item Number
Ab170948
Grouped product items
SKU Size
Availability
Price Qty
Ab170948-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170948-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$237.90
Ab170948-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$597.90
Ab170948-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$957.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Tinurilimab (anti-CEACAM6) - Primary antibody, specific to CEACAM6, >95%, high purity, Human IgG2
Synonyms Carcinoembryonic antigen related cell adhesion molecule 6 antibody | Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen) antibody | Carcinoembryonic antigen-related cell adhesion molecule 6 antibody | CD 66c ant
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CEACAM6
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Tinurilimab (anti-CEACAM6) is an anti-CEACAM6 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG2
Light Chain Type kappa
SDS-PAGE 26.2 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 165.6 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2226224-30-0

Associated Targets(Human)

CEACAM6 Tbio Carcinoembryonic antigen-related cell adhesion molecule 6 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Tinurilimab (anti-CEACAM6) (Ab170948) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling CEACAM6 (red) with Tinurilimab (anti-CEACAM6) (Ab170948). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Tinurilimab (anti-CEACAM6) (Ab170948) - SEC
The purity of Tinurilimab (anti-CEACAM6) (Ab170948) is more than 95% verified by HPLC.

Tinurilimab (anti-CEACAM6) (Ab170948) - ELISA
Immobilized CEACAM6-ECD-his at 2 μg/mL can bind Tinurilimab (anti-CEACAM6) (Ab170948) with the EC₅₀ of 5.42 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001517 Certificate of Analysis Nov 02, 2023 Ab170948
ZJ23F1001516 Certificate of Analysis Nov 02, 2023 Ab170948

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