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TA136 (anti-MPL) - Primary antibody, specific to MPL, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209754
Grouped product items
SKU Size
Availability
Price Qty
Ab209754-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209754-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209754-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209754-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name TA136 (anti-MPL) - Primary antibody, specific to MPL, Human IgG1
Synonyms C MPL antibody | CD110 antibody | mpl antibody | MPLV antibody | Myeloproliferative leukemia protein antibody | Myeloproliferative leukemia virus oncogene antibody | Proto-oncogene c-Mpl antibody | THCYT2 antibody | Thrombopoietin receptor antibody | TPO
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Host species Human
Specificity MPL
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

TA136 (anti-MPL) is antibody binds to MPL and recognizes a tertial structure of MPL. It can be potentially used in the treatment of congenital amegakaryocytic thrombocytopenia.

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

MPL Tclin Thrombopoietin receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

TA136 (anti-MPL) (Ab209754) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling MPL (red) with TA136 (anti-MPL) (Ab209754) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (Cy5) (Ab175833) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

TA136 (anti-MPL) (Ab209754) - Flow
Flow Cytometry analysis of pLVX-puro-P40238-hu-MPL/TPOR/CD110-FL cells at 1×105 cell/well can bind TA136 (anti-MPL) (Ab209754), with the EC₅₀ is 0.3 nM.

TA136 (anti-MPL) (Ab209754) - SEC
The purity of TA136 (anti-MPL) (Ab209754) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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