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Spinophilin/Neurabin 2 Mouse mAb - Primary antibody, specific to PPP1R9B, Mouse IgG1

COA COA
    Application:
  • WB
  • Host species: Mouse
  • Reactive species: Human,Mouse,Rat
  • Isotype: Mouse IgG1
  • Clone Number: K94019_12A3
  • Conjugation: Unconjugated
In stock
Item Number
Ab129005
Grouped product items
SKU Size
Availability
 Price Qty
Ab129005-10μl
10μl
2
$69.90
Ab129005-50μl
50μl
1
$199.90
Ab129005-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab129005-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (K94019_12A3); Mouse anti Human Spinophilin/Neurabin 2 Antibody; WB; Unconjugated

View related series
Click to view target information: PPP1R9B
Accession#: Q96SB3 (1) Gene ID: 84687 (1) Neurabin 2 (1) PPP1R9B (1) Spinophilin (1)

Basic Description

Product Name Spinophilin/Neurabin 2 Mouse mAb - Primary antibody, specific to PPP1R9B, Mouse IgG1
Synonyms NEB2_HUMAN antibody | Neurabin II antibody | Neurabin-2 antibody | Neurabin-II antibody | Neurabin2 antibody | NeurabinII antibody | Neural tissue specific F actin binding protein II antibody | p130 antibody | FLJ30345 antibody | PP1bp134 antibody | PPP1R
Specifications & Purity ExactAb™, Validated, Carrier Free, 1.0 mg/mL
Host species Mouse
Specificity PPP1R9B
Immunogen Recombinant protein of human Spinophilin/Neurabin 2 (AA 451-810)
Positive Control WB: Mouse brain, HEL, SK-N-SH, U-2 OS, MCF7, NIH/3T3 and C6 lysates.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human Spinophilin/Neurabin 2 Antibody, Monoclonal (K94019_12A3), could be used for WB and so on.
Application:
WB: 1/1000
Protein Function
Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity). Required for hepatocyte growth factor (HGF)-induced cell migration.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 1.0 mg/mL
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 2-8 ℃ (3 months). Store at -20 ℃ (12 months). Store at -80 ℃ (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PPP1R9B Tbio Neurabin-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Spinophilin/Neurabin 2 Mouse mAb (Ab129005) - Western Blot
All lanes: Spinophilin/Neurabin 2 Mouse mAb (Ab129005) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution

Predicted band size: 89 kDa
Observed band size: 110 kDa
Exposure time: 65.1 s

Application

Application Dilution info
WB

1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0708455 Certificate of Analysis Jul 17, 2024 Ab129005
ZJ24F0708454 Certificate of Analysis Jul 17, 2024 Ab129005

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