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Sibeprenlimab (anti-TNFSF13) - Primary antibody, specific to TNFSF13, >95%, high purity, Human IgG2SA, INHIBITOR of Tumor necrosis factor ligand superfamily member 13 inhibitor, INHIBITOR of Tumor necrosis factor ligand superfamily member 13 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG2SA
  • Conjugation: Unconjugated
In stock
Item Number
Ab176084
Grouped product items
SKU Size
Availability
Price Qty
Ab176084-100μg
100μg
10
$59.90
Ab176084-1mg
1mg
4
$289.90
Ab176084-5mg
5mg
1
$749.90
Ab176084-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Sibeprenlimab (anti-TNFSF13) - Primary antibody, specific to TNFSF13, >95%, high purity, Human IgG2SA, INHIBITOR of Tumor necrosis factor ligand superfamily member 13 inhibitor
Synonyms A proliferation-inducing ligand | APRIL | TALL-2 | TNF- and APOL-related leukocyte expressed ligand 2 | TNF-related death ligand 1 | TRDL-1
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFSF13
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Tumor necrosis factor ligand superfamily member 13 inhibitor
Product Description

Sibeprenlimab (anti-TNFSF13) is a humanized IgG2 monoclonal antibody. Sibeprenlimab (anti-TNFSF13) can inhibit APRIL. Sibeprenlimab (anti-TNFSF13) can be used for the research of IgA nephropathy (IgAN).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG2SA
Light Chain Type kappa
SDS-PAGE 27.4 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 175.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2382896-07-1

Associated Targets(Human)

TNFSF13 Tbio Tumor necrosis factor ligand superfamily member 13 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Sibeprenlimab (anti-TNFSF13) (Ab176084) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling TNFSF13 (red) with Sibeprenlimab (anti-TNFSF13) (Ab176084). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Sibeprenlimab (anti-TNFSF13) (Ab176084) - SEC
The purity of Sibeprenlimab (anti-TNFSF13) (Ab176084) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404250 Certificate of Analysis Apr 08, 2024 Ab176084
ZJ24F0404249 Certificate of Analysis Apr 08, 2024 Ab176084
ZJ24F0404248 Certificate of Analysis Apr 08, 2024 Ab176084

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