Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176084-100μg
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100μg |
10
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$59.90
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Ab176084-1mg
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1mg |
4
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$289.90
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Ab176084-5mg
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5mg |
1
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$749.90
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Ab176084-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,189.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Sibeprenlimab (anti-TNFSF13) - Primary antibody, specific to TNFSF13, >95%, high purity, Human IgG2SA, INHIBITOR of Tumor necrosis factor ligand superfamily member 13 inhibitor |
|---|---|
| Synonyms | A proliferation-inducing ligand | APRIL | TALL-2 | TNF- and APOL-related leukocyte expressed ligand 2 | TNF-related death ligand 1 | TRDL-1 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TNFSF13 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Tumor necrosis factor ligand superfamily member 13 inhibitor |
| Product Description |
Sibeprenlimab (anti-TNFSF13) is a humanized IgG2 monoclonal antibody. Sibeprenlimab (anti-TNFSF13) can inhibit APRIL. Sibeprenlimab (anti-TNFSF13) can be used for the research of IgA nephropathy (IgAN). |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.4 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 175.1 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2382896-07-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Sibeprenlimab (anti-TNFSF13) (Ab176084) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling TNFSF13 (red) with Sibeprenlimab (anti-TNFSF13) (Ab176084). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Sibeprenlimab (anti-TNFSF13) (Ab176084) - SEC
The purity of Sibeprenlimab (anti-TNFSF13) (Ab176084) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 08, 2024 | Ab176084 | |
| Certificate of Analysis | Apr 08, 2024 | Ab176084 | |
| Certificate of Analysis | Apr 08, 2024 | Ab176084 |