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SAR-113244 (anti-CXCR5) - Primary antibody, specific to CXCR5, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab190142
Grouped product items
SKU Size
Availability
Price Qty
Ab190142-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab190142-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab190142-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,299.90
Ab190142-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,079.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name SAR-113244 (anti-CXCR5) - Primary antibody, specific to CXCR5, Human IgG1
Synonyms BLR 1 antibody | BLR1 antibody | Burkitt lymphoma receptor 1 antibody | Burkitt lymphoma receptor 1 GTP binding protein antibody | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody | C X C chemokine receptor ty
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CXCR5
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

SAR-113244 (anti-CXCR5) is a humanized monoclonal antibody that specifically targets CXCR5. It can be used in the treatment of arthritis, autoimmune diseases, inflammatory diseases, graft rejection, and cancer .

Purity

≥95% (SDS-PAGE&SEC)

Endotoxin Level

≤1.0EU/mg

Protein Function

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. 

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 144.1 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CXCR5 Tchem C-X-C chemokine receptor type 5 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

SAR-113244 (anti-CXCR5) (Ab190142) - ELISA
Immobilized Recombinant Human CXCR5-VLP protein at 16.0 μg/mL can bind SAR-113244 (anti-CXCR5) (Ab190142) with the EC₅₀ of 17.12 ng/mL.

SAR-113244 (anti-CXCR5) (Ab190142) - SEC
The purity of SAR-113244 (anti-CXCR5) (Ab190142) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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