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Samalizumab (anti-CD200) - Primary antibody, specific to CD200, >95% (SDS-PAGE&SEC), high purity, Human IgG2SA, INHIBITOR of OX-2 membrane glycoprotein inhibitor, INHIBITOR of OX-2 membrane glycoprotein inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG2SA
  • Conjugation: Unconjugated
In stock
Item Number
Ab183431
Grouped product items
SKU Size
Availability
Price Qty
Ab183431-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab183431-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab183431-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$689.90
Ab183431-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Samalizumab (anti-CD200) - Primary antibody, specific to CD200, >95% (SDS-PAGE&SEC), high purity, Human IgG2SA, INHIBITOR of OX-2 membrane glycoprotein inhibitor
Synonyms Antigen identified by monoclonal antibody MRC OX 2 antibody | CD200 antibody | CD200 antigen antibody | CD200 molecule antibody | MOX1 antibody | MOX2 antibody | MRC antibody | MRC OX 2 antigen antibody | My033 antibody | OX 2 antibody | OX 2 membrane gly
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Host species Human
Specificity CD200
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of OX-2 membrane glycoprotein inhibitor
Product Description

Samalizumab (anti-CD200) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab (anti-CD200) can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research.

Product Properties

Isotype Human IgG2SA
Light Chain Type kappa
SDS-PAGE 144.84 kDa
Purification Method Protein A purified
Purity >95% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1073059-33-2

Associated Targets(Human)

CD200 Tbio OX-2 membrane glycoprotein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Samalizumab (anti-CD200) (Ab183431) - Flow Cytometry
huCD200-FL-HEK293-A7 cells at 1 x 105 cell/well can bind Samalizumab (anti-CD200) (Ab183431) with the EC50 is 0.15 μg/mL.

Samalizumab (anti-CD200) (Ab183431) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD200 with Samalizumab (anti-CD200) (Ab183431) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Samalizumab (anti-CD200) (Ab183431) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD200 (red) with Samalizumab (anti-CD200) (Ab183431) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Samalizumab (anti-CD200) (Ab183431) - SEC
The purity of Samalizumab (anti-CD200) (Ab183431) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

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