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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183431-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab183431-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$289.90
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Ab183431-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$689.90
|
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Ab183431-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,239.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Samalizumab (anti-CD200) - Primary antibody, specific to CD200, >95% (SDS-PAGE&SEC), high purity, Human IgG2SA, INHIBITOR of OX-2 membrane glycoprotein inhibitor |
|---|---|
| Synonyms | Antigen identified by monoclonal antibody MRC OX 2 antibody | CD200 antibody | CD200 antigen antibody | CD200 molecule antibody | MOX1 antibody | MOX2 antibody | MRC antibody | MRC OX 2 antigen antibody | My033 antibody | OX 2 antibody | OX 2 membrane gly |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. |
| Host species | Human |
| Specificity | CD200 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of OX-2 membrane glycoprotein inhibitor |
| Product Description |
Samalizumab (anti-CD200) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab (anti-CD200) can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research. |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 144.84 kDa |
| Purification Method | Protein A purified |
| Purity | >95% (SDS-PAGE&SEC) |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1073059-33-2 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Samalizumab (anti-CD200) (Ab183431) - Flow Cytometry
huCD200-FL-HEK293-A7 cells at 1 x 105 cell/well can bind Samalizumab (anti-CD200) (Ab183431) with the EC50 is 0.15 μg/mL.
Samalizumab (anti-CD200) (Ab183431) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD200 with Samalizumab (anti-CD200) (Ab183431) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
Samalizumab (anti-CD200) (Ab183431) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD200 (red) with Samalizumab (anti-CD200) (Ab183431) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Samalizumab (anti-CD200) (Ab183431) - SEC
The purity of Samalizumab (anti-CD200) (Ab183431) is more than 95% verified by HPLC.