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Rosopatamab (anti-PSMA) - Primary antibody, specific to FOLH1, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab190122
Grouped product items
SKU Size
Availability
Price Qty
Ab190122-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab190122-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
Ab190122-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$879.90
Ab190122-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,409.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Rosopatamab (anti-PSMA) - Primary antibody, specific to FOLH1, Human IgG1
Synonyms Cell growth inhibiting protein 27 antibody | Cell growth-inhibiting gene 27 protein antibody | FGCP antibody | Folate hydrolase (prostate-specific membrane antigen) 1 antibody | Folate hydrolase 1 antibody | Folate hydrolase antibody | Folate hydrolase pr
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission t
Host species Human
Specificity FOLH1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Rosopatamab (anti-PSMA) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab (anti-PSMA) can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 144.36 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2260767-49-3

Associated Targets(Human)

FOLH1 Tclin Glutamate carboxypeptidase 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Rosopatamab (anti-PSMA) (Ab190122) - Flow Cytometry
Flow Cytometry analysis of LNCaP cells labelling PSMA (red) with Rosopatamab (anti-PSMA) (Ab190122) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Rosopatamab (anti-PSMA) (Ab190122) - Flow
pLVX-puro-SYMX05-Hu-PSMA(Q04609)-FL cells at 1×105 cell/well can bind Rosopatamab (anti-PSMA) (Ab190122), with the EC₅₀ of 226.8 ng/mL.

Rosopatamab (anti-PSMA) (Ab190122) - SEC
The purity of Rosopatamab (anti-PSMA) (Ab190122) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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