Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab190122-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$69.90
|
|
|
Ab190122-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$349.90
|
|
|
Ab190122-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$879.90
|
|
|
Ab190122-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,409.90
|
|
Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Rosopatamab (anti-PSMA) - Primary antibody, specific to FOLH1, Human IgG1 |
|---|---|
| Synonyms | Cell growth inhibiting protein 27 antibody | Cell growth-inhibiting gene 27 protein antibody | FGCP antibody | Folate hydrolase (prostate-specific membrane antigen) 1 antibody | Folate hydrolase 1 antibody | Folate hydrolase antibody | Folate hydrolase pr |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission t |
| Host species | Human |
| Specificity | FOLH1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Rosopatamab (anti-PSMA) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab (anti-PSMA) can be linked to the low-energy beta-emitting radioisotope lutetium-177 (177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 144.36 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2260767-49-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Rosopatamab (anti-PSMA) (Ab190122) - Flow Cytometry
Flow Cytometry analysis of LNCaP cells labelling PSMA (red) with Rosopatamab (anti-PSMA) (Ab190122) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Rosopatamab (anti-PSMA) (Ab190122) - Flow
pLVX-puro-SYMX05-Hu-PSMA(Q04609)-FL cells at 1×105 cell/well can bind Rosopatamab (anti-PSMA) (Ab190122), with the EC₅₀ of 226.8 ng/mL.
Rosopatamab (anti-PSMA) (Ab190122) - SEC
The purity of Rosopatamab (anti-PSMA) (Ab190122) is more than 95% verified by HPLC.
Starting at $109.90