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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209828-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$99.90
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Ab209828-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$469.90
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Ab209828-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,159.90
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Ab209828-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,899.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Rolinsatamab (anti-PRLR) - Primary antibody, specific to PRLR |
|---|---|
| Synonyms | AI987712 antibody | CLONE SPM213 antibody | CPRLP antibody | Delta 4-delta 7/11 truncated prolactin receptor antibody | Delta 4-SF1b truncated prolactin receptor antibody | HPRL antibody | hPRL receptor antibody | hPRLrI antibody | Lactogen receptor antib |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| Host species | Human |
| Specificity | PRLR |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Rolinsatamab (anti-PRLR) is a IgG1κ type chimeric antibody targeting to PRLR (prolactin receptor). Rolinsatamab (anti-PRLR) can be conjugated with pyrrolobenzodiazepine (PDB) dimer SGD-1882 via a cleavable maleimidocaproyl type linker, to form an antibody-drug conjugate, Rolinsatamab talirine. |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 145 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Rolinsatamab (anti-PRLR) (Ab209828) - ELISA
Immobilized Recombinant Human PRLR / Prolactin Receptor, Fc Tag protein at 2.0 μg/mL can bind Rolinsatamab (anti-PRLR) (Ab209828) with the EC50 of 23.03 ng/mL.
Rolinsatamab (anti-PRLR) (Ab209828) - SEC
The purity of Rolinsatamab (anti-PRLR) (Ab209828) is more than 95% verified by HPLC.
Starting at $109.90