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Rolinsatamab (anti-PRLR) - Primary antibody, specific to PRLR

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209828
Grouped product items
SKU Size
Availability
Price Qty
Ab209828-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
Ab209828-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$469.90
Ab209828-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,159.90
Ab209828-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,899.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Rolinsatamab (anti-PRLR) - Primary antibody, specific to PRLR
Synonyms AI987712 antibody | CLONE SPM213 antibody | CPRLP antibody | Delta 4-delta 7/11 truncated prolactin receptor antibody | Delta 4-SF1b truncated prolactin receptor antibody | HPRL antibody | hPRL receptor antibody | hPRLrI antibody | Lactogen receptor antib
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Host species Human
Specificity PRLR
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Rolinsatamab (anti-PRLR) is a IgG1κ type chimeric antibody targeting to PRLR (prolactin receptor). Rolinsatamab (anti-PRLR) can be conjugated with pyrrolobenzodiazepine (PDB) dimer SGD-1882 via a cleavable maleimidocaproyl type linker, to form an antibody-drug conjugate, Rolinsatamab talirine.

Product Properties

Light Chain Type kappa
SDS-PAGE 145 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PRLR Tbio Prolactin receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Rolinsatamab (anti-PRLR) (Ab209828) - ELISA
Immobilized Recombinant Human PRLR / Prolactin Receptor, Fc Tag protein at 2.0 μg/mL can bind Rolinsatamab (anti-PRLR) (Ab209828) with the EC50 of 23.03 ng/mL.

Rolinsatamab (anti-PRLR) (Ab209828) - SEC
The purity of Rolinsatamab (anti-PRLR) (Ab209828) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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