Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183026-100μg
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100μg |
10
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$159.90
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Ab183026-1mg
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1mg |
4
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$799.90
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Ab183026-5mg
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5mg |
1
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$1,999.90
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Ab183026-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$3,199.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Reslizumab (anti-IL-5) - Primary antibody, specific to IL5, Human IgG4, INHIBITOR of Interleukin-5 inhibitor |
|---|---|
| Synonyms | B-cell differentiation factor I antibodyColony stimulating factor antibody | EDF antibody | Eosinophil differentiation factor antibody | IL-5 antibody | IL5 antibody | IL5_HUMAN antibody | Interleukin 5 (colony stimulating factor, eosinophil) antibody | I |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL5 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interleukin-5 inhibitor |
| Product Description |
Reslizumab (anti-IL-5) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab (anti-IL-5) is effective in neutralizing the function of IL-5. Reslizumab (anti-IL-5) has high binding affinity for human IL-5, with KD values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively. |
| Isotype | Human IgG4 |
|---|---|
| Light Chain Type | kappa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 241473-69-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Reslizumab (anti-IL-5) (Ab183026) - ELISA
Immobilized hu-IL-5-His at 2.0 μg/mL can bind Reslizumab (anti-IL-5) (Ab183026) with the EC
₅₀
of 41.32 ng/mL.
Reslizumab (anti-IL-5) (Ab183026) - SEC
The purity of Reslizumab (anti-IL-5) (Ab183026) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jul 24, 2024 | Ab183026 | |
| Certificate of Analysis | Jul 24, 2024 | Ab183026 | |
| Certificate of Analysis | Jul 24, 2024 | Ab183026 |
Starting at $109.90
Starting at $89.90
Starting at $109.90