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Reslizumab (anti-IL-5) - Primary antibody, specific to IL5, Human IgG4, INHIBITOR of Interleukin-5 inhibitor, INHIBITOR of Interleukin-5 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG4
  • Conjugation: Unconjugated
In stock
Item Number
Ab183026
Grouped product items
SKU Size
Availability
Price Qty
Ab183026-100μg
100μg
10
$159.90
Ab183026-1mg
1mg
4
$799.90
Ab183026-5mg
5mg
1
$1,999.90
Ab183026-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,199.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Reslizumab (anti-IL-5) - Primary antibody, specific to IL5, Human IgG4, INHIBITOR of Interleukin-5 inhibitor
Synonyms B-cell differentiation factor I antibodyColony stimulating factor antibody | EDF antibody | Eosinophil differentiation factor antibody | IL-5 antibody | IL5 antibody | IL5_HUMAN antibody | Interleukin 5 (colony stimulating factor, eosinophil) antibody | I
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL5
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Interleukin-5 inhibitor
Product Description

Reslizumab (anti-IL-5) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab (anti-IL-5) is effective in neutralizing the function of IL-5. Reslizumab (anti-IL-5) has high binding affinity for human IL-5, with KD values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4
Light Chain Type kappa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 241473-69-8

Associated Targets(Human)

IL5 Tclin Interleukin-5 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Reslizumab (anti-IL-5) (Ab183026) - ELISA
Immobilized hu-IL-5-His at 2.0 μg/mL can bind Reslizumab (anti-IL-5) (Ab183026) with the EC ₅₀ of 41.32 ng/mL.

Reslizumab (anti-IL-5) (Ab183026) - SEC
The purity of Reslizumab (anti-IL-5) (Ab183026) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0708696 Certificate of Analysis Jul 24, 2024 Ab183026
ZJ24F0708695 Certificate of Analysis Jul 24, 2024 Ab183026
ZJ24F0708694 Certificate of Analysis Jul 24, 2024 Ab183026

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