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Recombinant Transferrin Receptor Antibody - Primary antibody, specific to Transferrin Receptor, Mouse IgG2b

COA COA
    Application:
  • IHC
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG2b
  • Clone Number: 10F11
  • Conjugation: Unconjugated
In stock
Item Number
Ab132243
Grouped product items
SKU Size
Availability
 Price Qty
Ab132243-10μl
10μl
2
$39.90
Ab132243-50μl
50μl
1
$119.90
Ab132243-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab132243-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,799.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant (10F11); Mouse anti Human Transferrin Receptor Antibody; IHC; Unconjugated

View related series
Click to view target information: TFRC
Accession#: P02786 (14) CD71 (21) Gene ID: 7037 (14) Transferrin Receptor (8)

Basic Description

Product Name Recombinant Transferrin Receptor Antibody - Primary antibody, specific to Transferrin Receptor, Mouse IgG2b
Synonyms CD 71 antibody | CD71 antibody | CD71 antigen antibody | IMD46 antibody | OTTHUMP00000208523 antibody | OTTHUMP00000208524 antibody | OTTHUMP00000208525 antibody | p90 antibody | sTfR antibody | T9 antibody | TFR 1 antibody | TfR antibody | TfR1 antibody
Specifications & Purity ExactAb™, Validated, Carrier Free, Recombinant, 0.042 mg/mL
Host species Mouse
Specificity Transferrin Receptor
Immunogen Prokaryotic recombinant protein corresponding to a region of the N-terminal intracellular domain of the human CD71.
Positive Control IHC: Human placenta tissue.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Recombinant, Validated
Product Description

Mouse anti Human Transferrin Receptor Antibody, Recombinant (10F11), could be used for IHC and so on.

Application

  • IHC: 1/50-1/100

Protein Function

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed:26642240).

(Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus.

Product Properties

Isotype Mouse IgG2b
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.042 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

TFRC Tclin Transferrin receptor protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TFRC Tclin Transferrin receptor protein 1 (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Transferrin Receptor Antibody (Ab132243) - IHC
Immunohistochemistry analysis of paraffin-embedded human placenta tissue labelling Transferrin Receptor with Recombinant Transferrin Receptor Antibody (Ab132243) at 1/50 dilution. The section was incubated with Ab132243 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Application

Application Dilution info
IHC

1/50-1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505385 Certificate of Analysis May 11, 2024 Ab132243
ZJ24F0505384 Certificate of Analysis May 11, 2024 Ab132243

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