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Recombinant pan Cytokeratin Antibody - Primary antibody, specific to pan Cytokeratin, Mouse IgG

COA COA
    Application:
  • IHC
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG
  • Clone Number: AE1/AE3
  • Conjugation: Unconjugated
In stock
Item Number
Ab120149
Grouped product items
SKU Size
Availability
 Price Qty
Ab120149-10μl
10μl
2
$69.90
Ab120149-50μl
50μl
1
$209.90
Ab120149-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
Ab120149-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,299.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant (AE1/AE3); Mouse anti Human pan Cytokeratin Antibody; IHC; Unconjugated

View related series
Click to view target information: KRT76 Click to view target information: KRT77
Accession#: Q01546 (1) Accession#: Q7Z794 (1) Gene ID: 374454 (1) Gene ID: 51350 (1) KRT76 (1) KRT77 (1) pan Cytokeratin (1)

Basic Description

Product Name Recombinant pan Cytokeratin Antibody - Primary antibody, specific to pan Cytokeratin, Mouse IgG
Synonyms pan ck antibody | pan-ck antibody | panck antibody
Specifications & Purity ExactAb™, Validated, Carrier Free, Recombinant, 0.0125 mg/mL
Host species Mouse
Specificity pan Cytokeratin
Immunogen Purified full length native protein corresponding to Human pan Cytokeratin.
Positive Control IHC: Human breast cancer tissue.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Recombinant, Validated
Product Description

Mouse anti Human pan Cytokeratin Antibody, Recombinant (AE1/AE3), could be used for IHC and so on.
Application
IHC: 1/50-1/100
Relevance
Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.

Product Properties

Isotype Mouse IgG
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.0125 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

KRT76 Tdark Keratin, type II cytoskeletal 2 oral (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
KRT77 Tbio Keratin, type II cytoskeletal 1b (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant pan Cytokeratin Antibody (Ab120149) - IHC
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue labelling pan Cytokeratin with Recombinant pan Cytokeratin Antibody (Ab120149) at 1/100 dilution. The section was incubated with Ab120149 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Application

Application Dilution info
IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0506370 Certificate of Analysis May 31, 2024 Ab120149
ZJ24F0404743 Certificate of Analysis Apr 22, 2024 Ab120149
ZJ24F0404742 Certificate of Analysis Apr 22, 2024 Ab120149

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