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Recombinant Integrin beta 3 Antibody - Primary antibody, specific to Integrin beta 3, Mouse IgG1

COA COA
    Application:
  • IHC
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: MyM1-CD61
  • Conjugation: Unconjugated
In stock
Item Number
Ab110871
Grouped product items
SKU Size
Availability
 Price Qty
Ab110871-10μl
10μl
5
$69.90
Ab110871-50μl
50μl
2
$199.90
Ab110871-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab110871-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant (MyM1-CD61); Mouse anti Human Integrin beta 3 Antibody; IHC; Unconjugated

View related series
Click to view target information: ITGB3
Accession#:P05106 (9) CD61 (7) Gene ID:3690 (9) Integrin beta 3 (5) ITGB3 (9)

Basic Description

Product Name Recombinant Integrin beta 3 Antibody - Primary antibody, specific to Integrin beta 3, Mouse IgG1
Synonyms BDPLT16 antibody | BDPLT2 antibody | CD 61 antibody | CD61 antibody | CD61 antigen antibody | GP3A antibody | GPIIIa antibody | GT antibody | HPA 1 antibody | HPA 4 antibody | Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody | Integrin b
Specifications & Purity ExactAb™, Validated, Recombinant, 0.04 mg/mL
Host species Mouse
Specificity Integrin beta 3
Positive Control IHC: Human spleen tissue.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Mouse anti Human Integrin beta 3 Antibody, Recombinant (MyM1-CD61), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.04 mg/mL
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Store at 2-8°C long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ITGB3 Tclin Integrin beta-3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ITGB3 Tclin Integrin alpha-V/beta-3 (2708 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-IIb/beta-3 (3481 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) (39 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 and alpha-IIb/beta 3 (49 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-2/beta-3 (21 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-3/beta-3 (47 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Integrin beta 3 Antibody (Ab110871) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Integrin beta 3 with Recombinant Integrin beta 3 Antibody (Ab110871) at 1/100 dilution. The section was incubated with Ab110871 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Application

Application Dilution info
IHC

1/100 - 1/200

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505254 Certificate of Analysis May 09, 2024 Ab110871
ZJ24F0505253 Certificate of Analysis May 09, 2024 Ab110871

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