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Recombinant CD45 Antibody - Primary antibody, specific to CD45, Mouse IgG

    Application:
  • IHC
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG
  • Clone Number: 2B11&PD7/26
  • Conjugation: Unconjugated
In stock
Item Number
Ab006747
Grouped product items
SKU Size
Availability
Price Qty
Ab006747-10μl
10μl
2
$29.90
Ab006747-50μl
50μl
1
$99.90
Ab006747-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$149.90
Ab006747-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,259.90

Recombinant (2B11&PD7/26); Mouse anti Human CD45 Antibody; IHC; Unconjugated

Basic Description

Product Name Recombinant CD45 Antibody - Primary antibody, specific to CD45, Mouse IgG
Synonyms B220 antibody | CD 45 antibody | CD45 antibody | CD45 antigen antibody | CD45R antibody | GP180 antibody | L-CA antibody | LCA antibody | Leukocyte common antigen antibody | loc antibody | Ly-5 antibody | LY5 antibody | Ly5, homolog of antibody | Lyt-4 an
Specifications & Purity ExactAb™, Validated, Carrier Free, Recombinant, 0.45 mg/mL
Host species Mouse
Specificity CD45
Immunogen Synthetic peptide corresponding to CD45. Human peripheral blood lymphocytes were used to raise clone PD7/26 and isolated neoplastic cells from a T cell lymphoma were used to raise clone 2B11.
Positive Control IHC: Human tonsil tissue.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Recombinant, Validated
Product Description

Mouse anti Human CD45 Antibody, Recombinant (2B11&PD7/26), could be used for IHC and so on.
Application
IHC: 1/50-1/100
Protein Function
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.

Product Properties

Isotype Mouse IgG
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.45 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PTPRC Tchem Receptor-type tyrosine-protein phosphatase C (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant CD45 Antibody (Ab006747) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling CD45 with Recombinant CD45 Antibody (Ab006747) at 1/100 dilution. The section was incubated with Ab006747 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Application

Application Dilution info
IHC

1/50 - 1/100

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505363 Certificate of Analysis May 10, 2024 Ab006747
ZJ24F0505362 Certificate of Analysis May 10, 2024 Ab006747

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