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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170952-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$79.90
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Ab170952-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$387.90
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Ab170952-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$777.90
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Ab170952-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,227.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Prezalumab (anti-B7-H2) - Primary antibody, specific to ICOSLG, >95%, high purity, Human IgG2SA |
|---|---|
| Synonyms | B7 H2 antibody | B7 homolog 2 antibody | B7 homologue 2 antibody | B7 like protein Gl50 antibody | B7 related protein 1 antibody | B7-H2 antibody | B7-like protein Gl50 antibody | B7-related protein 1 antibody | B7H2 antibody | B7RP 1 antibody | B7RP-1 an |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | ICOSLG |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Prezalumab (anti-B7-H2) is a humanized IgG2 monoclonal antibody targets ICOSL and BAFF. Prezalumab (anti-B7-H2) demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab (anti-B7-H2) can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE). |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 172.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1523164-68-2 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Prezalumab (anti-B7-H2) (Ab170952) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling B7-H2 (red) with Prezalumab (anti-B7-H2) (Ab170952). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Prezalumab (anti-B7-H2) (Ab170952) - SEC
The purity of Prezalumab (anti-B7-H2) (Ab170952) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 18, 2023 | Ab170952 | |
| Certificate of Analysis | Oct 18, 2023 | Ab170952 |