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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175634-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab175634-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
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Ab175634-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,319.90
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Ab175634-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,099.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Plozalizumab (anti-CCR2) - Primary antibody, specific to CCR2, >95%, high purity, Human IgG1, Antibody of CCR2 |
|---|---|
| Synonyms | C C chemokine receptor type 2 antibody | C C CKR 2 antibody | C-C chemokine receptor type 2 antibody | C-C CKR-2 antibody | CC chemokine receptor type 2 antibody | CC CKR 2 antibody | CC-CKR-2 antibody | CCCKR2 antibody | CCR 2 antibody | CCR-2 antibody | |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CCR2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | Antibody of CCR2 |
| Product Description |
Plozalizumab (anti-CCR2) is a specific humanized anti-CCR2 antibody. Plozalizumab (anti-CCR2) can be used for malignant melanoma research. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.5 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 180.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1610761-46-0 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Plozalizumab (anti-CCR2) (Ab175634) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling CCR2 (red) with Plozalizumab (anti-CCR2) (Ab175634). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Plozalizumab (anti-CCR2) (Ab175634) - SEC
The purity of Plozalizumab (anti-CCR2) (Ab175634) is more than 95% verified by HPLC.
Plozalizumab (anti-CCR2) (Ab175634) - Flow Cytometry
Flow Cytometry analysis of Human CCR2 HEK293 cells can bind Plozalizumab (anti-CCR2) (Ab175634) with the EC₅₀ of 50 nM.