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PharmPure™ GMP Portfolio

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  1. Recombinant Kex2 Protease
    Cas Number: 99676-46-7
      Species: Baker's yeast    Accession #: P13134    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Specific Activity: ≥10U/mg pro. UNIT DEFINITION: Under the conditions of 25°C and pH 8.0, the amount of enzyme needed to catalyze the conversion of 1 μmol Boc-QR R-pNA into products per minute is one enzyme activity unit (U).    
    Synonyms: KEX 2 | Kex2p | Kexin | KEX2 | QDS1 | SRB1 | VMA45
  2. Recombinant Human TNF-alpha Protein
      Species: Human    Accession #: P01375    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.    
    Synonyms: APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
  3. Recombinant Human EGF Protein
    Cas Number: 62253-63-8        Compound CID:  16143379
    Formula:  C270H401N73O83S7        Molecular Weight: 6.5kD
      Species: Human    Accession #: P01133    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.2 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <0.9 ng/mL.    
    IUPAC Name:  (4S)-5-[[(2S)-1-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-4-carbamimidshow more
    SMILES:  CCC(C)C(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(Cshow more
    InChIKey: GVUGOAYIVIDWIO-UFWWTJHBSA-N
    InChI:  InChI=1S/C270H401N73O83S7/c1-24-134(19)217(262(420)293-112-201(355)298-161(69-74-205(359)360)229(387)301-160(45-35-82-286-269(279)280)228(386)333-192(show more
    Synonyms: beta-urogastrone | EGF | epidermal growth factor (beta-urogastrone) | epidermal growth factor | hEGF | HOMG4 | pro-ep...
  4. Recombinant Human FGF basic/FGF2/bFGF(155aa) Protein
    Cas Number: 62031-54-3
    Formula:         Molecular Weight: 17kD
      Species: Human    Accession #: P09038    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.2 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <0.9 ng/mL.    
    Synonyms: Basic fibroblast growth factor Basic fibroblast growth factor bFGF BFGF FGF 2 FGF B FGF-2 Fgf2 FGF2 basic FGF2_HUMAN ...
  5. Recombinant Human EGF Protein
    Cas Number: 62253-63-8        Compound CID:  16143379
    Formula:  C270H401N73O83S7        Molecular Weight: 6.5kD
      Species: Human    Accession #: P01133    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.    
    IUPAC Name:  (4S)-5-[[(2S)-1-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-4-carbamimidshow more
    SMILES:  CCC(C)C(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(Cshow more
    InChIKey: GVUGOAYIVIDWIO-UFWWTJHBSA-N
    InChI:  InChI=1S/C270H401N73O83S7/c1-24-134(19)217(262(420)293-112-201(355)298-161(69-74-205(359)360)229(387)301-160(45-35-82-286-269(279)280)228(386)333-192(show more
    Synonyms: Recombinant Human Epidermal Growth Factor | rhEGF | beta-urogastrone | EGF | epidermal growth factor (beta-urogastron...
  6. Recombinant Human Flt-3 Ligand/FLT3L GMP Protein
      Species: Human    Accession #: P49771    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using OCI-AML5 acute myeloid leukemia cells. The ED50 for this effect is 0.200-2.00 ng/mL. The specific activity of Recombinant Human Flt-3 Ligand/FLT3L is >5.00 x 10^5 units/mg, which is calibrated against the human Flt-3 Ligand WHO standard (NIBSC code: 96/532).    
    Synonyms: fms-like Tyrosine Kinase 3 Ligand | FL | FLG3L | Flt3 ligand | Flt-3 Ligand | Flt3L | FLT3LG | fms-related tyrosine k...
  7. Recombinant Human FGF basic/FGF2/bFGF GMP Protein
      Species: Human    Accession #: P09038-4    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 0.100-1.00 ng/mL. The specific activity of Recombinant Human FGF basic/FGF2 GMP is >8.0 x 10^5 IU/mg, which is calibrated against the human FGF basic/FGF2 WHO International Standard (NIBSC code: 90/712).    
    Synonyms: Fibroblast Growth Factor basic | basic fibroblast growth factor bFGF | Basic fibroblast growth factor | bFGF | FGF ba...
  8. Recombinant Human EGF GMP Protein
      Species: Human    Accession #: P01133-1    
      Expression system: E. coli    Protein Tag: No tag/C-His tag    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 20‑100 pg/mL. The specific activity of Recombinant Human EGF is >8.0 x 10^5 IU/mg, which is calibrated against the human EGF WHO International Standard (NIBSC code: 91/530).    
    Synonyms: Epidermal Growth Factor | beta-urogastrone | EGF | epidermal growth factor (beta-urogastrone) | hEGF | HOMG4 | pro-ep...
  9. Recombinant Human BMP-4 GMP Protein
      Species: Human    Accession #: P12644    
      Expression system: E. coli    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Alkaline phosphatase production by ATDC-5 cells. ED50 approximately 95 ng/mL.    
    Synonyms: Bone Morphogenetic Protein 4 | BMP2B | BMP-2B | BMP2B1 | MCOPS6 | BMP4 | BMP-4 | Bone morphogenetic protein 2B | DVR4...
  10. Recombinant Human IL-1 beta/IL-1F2 GMP Protein
      Species: Human    Accession #: P01584    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is <12 pg/mL. The specific activity of recombinant human IL-1 beta is >5.0 x 10^7 IU/mg, which is calibrated against the human IL-1 beta WHO International Standard (NIBSC code: 86/680).    
    Synonyms: Interleukin 1 beta | catabolin | IL1 beta | IL-1 beta | IL-1 | IL1B | IL-1b | IL1-BETA | IL-1F2 | IL1F2 | interleukin...
  11. Recombinant Human GM-CSF GMP Protein
      Species: Human    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is 6-30 pg/mL. The specific activity of recombinant human GM-CSF is >1.0 x 10^7 IU/mg, which is calibrated against the human GM-CSF WHO International Standard (NIBSC code: 88/646).    
    Synonyms: Granulocyte Macrophage Growth Factor | colony stimulating factor 2 (granulocyte-macrophage) | Colony-stimulating fact...
  12. Recombinant Human IL-3 GMP Protein
      Species: Human    Accession #: AAC08706.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.02-0.1 ng/mL. The specific activity of recombinant human IL-3 is >1.7 x 10^6 IU/mg, which is calibrated against the human IL-3 WHO International Standard(NIBSC code: 91/510).    
    Synonyms: Hematopoietic growth factor | IL3 | IL-3 | IL-3MGC79398 | interleukin 3 (colony-stimulating factor, multiple) | inter...
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