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Otelixizumab (anti-CD3) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD3D, >95%, high purity, Human IgG1, Antibody of CD3e, Antibody of CD3e

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170522
Grouped product items
SKU Size
Availability
Price Qty
Ab170522-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab170522-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$447.90
Ab170522-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,107.90
Ab170522-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,797.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Otelixizumab (anti-CD3) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD3D, >95%, high purity, Human IgG1, Antibody of CD3e
Synonyms Anti-CD3 Reference Antibody (otelixizumab) | Otelixizumab | ChAglyCD3 | TRX 4 | 4930549J05Rik antibody | A430104F18Rik antibody | AW552088 antibody | Cd247 antibody | CD247 antigen antibody | CD247 antigen, zeta subunit antibody | CD247 molecule antibody
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD3D
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action Antibody of CD3e
Product Description

Otelixizumab (anti-CD3) is a recombinant monoclonal antibody to CD3. Otelixizumab is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes.
Purity:>95% (SDS-PAGE&SEC)
Endotoxin Level:< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type lambdaC2
SDS-PAGE 27.0 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 181.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 881191-44-2

Associated Targets(Human)

CD3D Tclin T-cell surface glycoprotein CD3 delta chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Otelixizumab (anti-CD3) (Ab170522) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 with Otelixizumab (anti-CD3) (Ab170522) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Otelixizumab (anti-CD3) (Ab170522) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 (red) with Otelixizumab (anti-CD3) (Ab170522) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Otelixizumab (anti-CD3) (Ab170522) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Otelixizumab (anti-CD3) (Ab170522). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Otelixizumab (anti-CD3) (Ab170522) - SEC
The purity of Otelixizumab (anti-CD3) (Ab170522) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001498 Certificate of Analysis Nov 02, 2023 Ab170522
ZJ23F1001497 Certificate of Analysis Nov 02, 2023 Ab170522

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