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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170578-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$109.90
|
|
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Ab170578-1mg
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1mg |
5
|
$507.90
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|
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Ab170578-5mg
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5mg |
1
|
$1,257.90
|
|
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Ab170578-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,857.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Oleclumab (anti-CD73) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to NT5E, >95%, high purity, Human IgG1, Antibody of Ecto-5'-Nucleotidase |
|---|---|
| Synonyms | 5'-NT | EC 3.1.3.5 | Ecto-5'-nucleotidase |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | NT5E |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | Antibody of Ecto-5'-Nucleotidase |
| Product Description |
Oleclumab (anti-NT5E) is a human IgG1λ anti-CD73 monoclonal antibody that inhibits CD73 function. Oleclumab has an anti-tumor activity. Purity |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | lambda |
| SDS-PAGE | 28.1 kDa (Light Chain) & 50.0 kDa (Heavy Chain), under reducing conditions; 172.2 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1803176-05-7 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Oleclumab (anti-CD73) (Ab170578) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling CD73 (red) with Oleclumab (anti-CD73) (Ab170578). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Oleclumab (anti-CD73) (Ab170578) - SEC
The purity of Oleclumab (anti-CD73) (Ab170578) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 06, 2023 | Ab170578 | |
| Certificate of Analysis | Dec 06, 2023 | Ab170578 |
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