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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab190147-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab190147-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$279.90
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Ab190147-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$789.90
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Ab190147-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,269.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | NTX-1088 (anti-PVR) - Primary antibody, specific to PVR, Human IgG1 |
|---|---|
| Synonyms | CD155 antibody | CD155 antigen antibody | FLJ25946 antibody | HVED antibody | mE4 antibody | NECL 5 antibody | Necl-5 antibody | Necl5 antibody | Nectin like 5 antibody | Nectin like protein 5 antibody | Nectin-like protein 5 antibody | Ortholog of mouse |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | PVR |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
NTX-1088 (anti-PVR) is a first-in-class potent monoclonal antibody targeting poliovirus receptor. It can be used in treatment of patients with locally advanced and metastatic solid tumors. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.86 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NTX-1088 (anti-PVR) (Ab190147) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling CD30 (red) with NTX-1088 (anti-PVR) (Ab190147). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
NTX-1088 (anti-PVR) (Ab190147) - Flow Cytometry
Flow Cytometry analysis of U937 cells labelling CD30 (red) with NTX-1088 (anti-PVR) (Ab190147). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
NTX-1088 (anti-PVR) (Ab190147) - SEC
The purity of NTX-1088 (anti-PVR) (Ab190147) is more than 95% verified by HPLC.