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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183134-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab183134-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab183134-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab183134-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,239.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | MEDI-3617 (anti-ANGPT2) - Primary antibody, specific to ANGPT2, Human IgG2SA, INHIBITOR of Angiopoietin-2 inhibitor |
|---|---|
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | ANGPT2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Angiopoietin-2 inhibitor |
| Product Description |
MEDI-3617 (anti-ANGPT2) is a human monoclonal antibody directed against the angiogenic cytokines angiopoietin-2 (Angpt2). MEDI-3617 (anti-ANGPT2) in combination with tremelimumab is used to treat advanced melanoma. |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | kappa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
MEDI-3617 (anti-ANGPT2) (Ab183134) - ELISA
Immobilized human ANGPT2-chis at 2.0 μg/mL can bind MEDI-3617 (anti-ANGPT2) (Ab183134) with the EC50 of 31.65 ng/mL.
MEDI-3617 (anti-ANGPT2) (Ab183134) - SEC
The purity of MEDI-3617 (anti-ANGPT2) (Ab183134) is more than 95% verified by HPLC.
Starting at $49.90
Starting at $59.90