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Lipocalin-2/NGAL Mouse mAb - Primary antibody, specific to LCN2, Mouse IgG1

COA COA
    Application:
  • WB
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: J13
  • Conjugation: Unconjugated
In stock
Item Number
Ab113231
Grouped product items
SKU Size
Availability
 Price Qty
Ab113231-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$66.90
Ab113231-50μl
50μl
4
$189.90
Ab113231-100μl
100μl
3
$299.90
Ab113231-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,019.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (J13); Mouse anti Human Lipocalin-2/NGAL Antibody; WB; Unconjugated

View related series
Click to view target information: LCN2
Accession#:P80188 (4) Gene ID:3934 (4) LCN2 (5) Lipocalin-2 (3) NGAL (4)

Basic Description

Product Name Lipocalin-2/NGAL Mouse mAb - Primary antibody, specific to LCN2, Mouse IgG1
Synonyms 24p3 | 25 kDa alpha-2-microglobulin-related subunit of MMP-9 | HNL | LCN2 | lipocalin 2 (oncogene 24p3) | lipocalin 2 | Lipocalin2 | Lipocalin-2 | migration-stimulating factor inhibitor | MSFI | neutrophil gelatinase-associated lipocalin | NGAL | NGALlipo
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, See COA
Host species Mouse
Specificity LCN2
Immunogen Recombinant NGALexpressed in E.coli (AA 21-198)
Positive Control WB: HT-29, A431 and LNCaP cell lysates.
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human Lipocalin-2 / NGAL Antibody, Monoclonal (J13), could be used for WB and so on.

Application:

WB: 0.5-2µg/mL

Protein Function

Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A + Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

LCN2 Tbio Neutrophil gelatinase-associated lipocalin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Lipocalin-2/NGAL Mouse mAb (Ab113231) - Western Blot
All lanes: Lipocalin-2/NGAL Mouse mAb (Ab113231) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 23 kDa
Observed band size: 23 kDa
Exposure time: 12.5 s

Application

Application Dilution info
WB

0.5-2µg/mL

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101837 Certificate of Analysis Nov 29, 2023 Ab113231
ZJ23F1101838 Certificate of Analysis Nov 29, 2023 Ab113231

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