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Metelimumab (anti-TGFb1) - Primary antibody, specific to TGFB1, Human IgG4, INHIBITOR of Transforming growth factor beta-1 inhibitor, INHIBITOR of Transforming growth factor beta-1 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG4
  • Conjugation: Unconjugated
In stock
Item Number
Ab183442
Grouped product items
SKU Size
Availability
Price Qty
Ab183442-100μg
100μg
10
$89.90
Ab183442-1mg
1mg
4
$419.90
Ab183442-5mg
5mg
1
$1,089.90
Ab183442-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,749.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Metelimumab (anti-TGFb1) - Primary antibody, specific to TGFB1, Human IgG4, INHIBITOR of Transforming growth factor beta-1 inhibitor
Synonyms Cartilage-inducing factor antibody | CED antibody | Differentiation inhibiting factor antibody | DPD1 antibody | LAP antibody | Latency-associated peptide antibody | Prepro transforming growth factor beta 1 antibody | TGF beta 1 antibody | TGF beta antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TGFB1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Transforming growth factor beta-1 inhibitor
Product Description

Metelimumab (anti-TGFb1) is a human IgG4 monoclonal antibody that can selectively neutralize TGFβ1.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4
Light Chain Type kappa
SDS-PAGE 25.7 kDa (Light Chain) & 52.9 kDa (Heavy Chain), under reducing conditions; 201.8 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 272780-74-2

Associated Targets(Human)

TGFB1 Tbio Transforming growth factor beta-1 proprotein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TGFB1 Tbio Transforming growth factor beta-1 (34 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Metelimumab (anti-TGFb1) (Ab183442) - ELISA
Immobilized Human TGFb1-Fc Tag at 2.0 μg/mL can bind Metelimumab (anti-TGFb1) (Ab183442) with the EC ₅₀ of 3.43 ng/mL.

Metelimumab (anti-TGFb1) (Ab183442) - SEC
The purity of Metelimumab (anti-TGFb1) (Ab183442) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607562 Certificate of Analysis Jun 28, 2024 Ab183442
ZJ24F0607561 Certificate of Analysis Jun 28, 2024 Ab183442
ZJ24F0607560 Certificate of Analysis Jun 28, 2024 Ab183442

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