Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab182837-100μg
|
100μg |
10
|
$89.90
|
|
|
Ab182837-1mg
|
1mg |
4
|
$419.90
|
|
|
Ab182837-5mg
|
5mg |
1
|
$1,089.90
|
|
|
Ab182837-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,749.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Fianlimab (anti-LAG3) - Primary antibody, specific to LAG3, Human IgG4SP, INHIBITOR of Lymphocyte activation gene 3 protein inhibitor |
|---|---|
| Synonyms | CD223 antibody | CD223 antigen antibody | FDC protein antibody | LAG-3 antibody | Lag3 antibody | LAG3_HUMAN antibody | Lymphocyte activating 3 antibody | Lymphocyte activation gene 3 antibody | Lymphocyte activation gene 3 protein antibody | Protein FDC |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | LAG3 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Lymphocyte activation gene 3 protein inhibitor |
| Product Description |
Fianlimab (anti-LAG3) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.8 kDa (Light Chain) & 55.3 kDa (Heavy Chain), under reducing conditions; 206.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2126132-98-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Fianlimab (anti-LAG3) (Ab182837) - ELISA
Immobilized Recombinant Human LAG3 protein (rp176292) at 1.0 μg/mL can bind Fianlimab (anti-LAG3) (Ab182837) with the EC50 of 146.7 ng/mL.
Fianlimab (anti-LAG3) (Ab182837) - SEC
The purity of Fianlimab (anti-LAG3) (Ab182837) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 28, 2024 | Ab182837 | |
| Certificate of Analysis | Jun 28, 2024 | Ab182837 | |
| Certificate of Analysis | Jun 28, 2024 | Ab182837 |
Starting at $89.90
Starting at $109.90
Starting at $69.90
Starting at $79.90
Starting at $49.90