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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab191913-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab191913-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab191913-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab191913-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG4SP; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Miptenalimab (anti-LAG3) - Primary antibody, specific to LAG3 |
|---|---|
| Synonyms | CD223 antibody | CD223 antigen antibody | FDC protein antibody | LAG-3 antibody | Lag3 antibody | LAG3_HUMAN antibody | Lymphocyte activating 3 antibody | Lymphocyte activation gene 3 antibody | Lymphocyte activation gene 3 protein antibody | Protein FDC |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Involved in lymphocyte activation. Binds to HLA class-II antigens. |
| Host species | Human |
| Specificity | LAG3 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Miptenalimab (anti-LAG3) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3). Miptenalimab (anti-LAG3) blocks the interaction of LAG-3 with its ligand MHC-II. |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 145.04 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2249882-55-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Miptenalimab (anti-LAG3) (Ab191913) - ELISA
Immobilized Recombinant Human LAG-3(C-6His) protein at 2.0 μg/mL can bind Miptenalimab (anti-LAG3) (Ab191913) with the EC50 of 28.79 ng/mL.
Miptenalimab (anti-LAG3) (Ab191913) - ELISA
Immobilized Recombinant Human LAG-3 (rp176292) protein at 1.0 μg/mL can bind Miptenalimab (anti-LAG3) (Ab191913) with the EC50 of 397.6 ng/mL.
Miptenalimab (anti-LAG3) (Ab191913) - SEC
The purity of Miptenalimab (anti-LAG3) (Ab191913) is more than 95% verified by HPLC.
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