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Miptenalimab (anti-LAG3) - Primary antibody, specific to LAG3

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab191913
Grouped product items
SKU Size
Availability
Price Qty
Ab191913-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab191913-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab191913-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,299.90
Ab191913-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,079.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG4SP; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Miptenalimab (anti-LAG3) - Primary antibody, specific to LAG3
Synonyms CD223 antibody | CD223 antigen antibody | FDC protein antibody | LAG-3 antibody | Lag3 antibody | LAG3_HUMAN antibody | Lymphocyte activating 3 antibody | Lymphocyte activation gene 3 antibody | Lymphocyte activation gene 3 protein antibody | Protein FDC
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Involved in lymphocyte activation. Binds to HLA class-II antigens.
Host species Human
Specificity LAG3
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Miptenalimab (anti-LAG3) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3). Miptenalimab (anti-LAG3) blocks the interaction of LAG-3 with its ligand MHC-II.

Product Properties

Light Chain Type kappa
SDS-PAGE 145.04 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2249882-55-9

Associated Targets(Human)

LAG3 Tclin Lymphocyte activation gene 3 protein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Miptenalimab (anti-LAG3) (Ab191913) - ELISA
Immobilized Recombinant Human LAG-3(C-6His) protein at 2.0 μg/mL can bind Miptenalimab (anti-LAG3) (Ab191913) with the EC50 of 28.79 ng/mL.

Miptenalimab (anti-LAG3) (Ab191913) - ELISA
Immobilized Recombinant Human LAG-3 (rp176292) protein at 1.0 μg/mL can bind Miptenalimab (anti-LAG3) (Ab191913) with the EC50 of 397.6 ng/mL.

Miptenalimab (anti-LAG3) (Ab191913) - SEC
The purity of Miptenalimab (anti-LAG3) (Ab191913) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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Solution Calculators

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