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Denintuzumab (anti-CD19) - Primary antibody, specific to CD19, >95%, high purity, Human IgG1, BINDING AGENT of B-lymphocyte antigen CD19 binding agent, BINDING AGENT of B-lymphocyte antigen CD19 binding agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170852
Grouped product items
SKU Size
Availability
Price Qty
Ab170852-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab170852-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$357.90
Ab170852-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$867.90
Ab170852-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,377.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Denintuzumab (anti-CD19) - Primary antibody, specific to CD19, >95%, high purity, Human IgG1, BINDING AGENT of B-lymphocyte antigen CD19 binding agent
Synonyms hBU 12 | Antibody deficiency due to defect in CD19 antibody | Antibody deficiency due to defect in CD19, included antibody | AW495831 antibody | B lymphocyte antigen CD19 antibody | B lymphocyte surface antigen B4 antibody | B-lymphocyte antigen CD19 anti
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD19
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of B-lymphocyte antigen CD19 binding agent
Product Description

Denintuzumab (anti-CD19) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab (anti-CD19) can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145.96 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1630074-14-4

Associated Targets(Human)

CD19 Tclin B-lymphocyte antigen CD19 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Denintuzumab (anti-CD19) (Ab170852) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD19 (red) with Denintuzumab (anti-CD19) (Ab170852). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Denintuzumab (anti-CD19) (Ab170852) - SEC
The purity of Denintuzumab (anti-CD19) (Ab170852) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0900971 Certificate of Analysis Sep 06, 2023 Ab170852
ZJ23F0900972 Certificate of Analysis Sep 06, 2023 Ab170852

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