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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182851-100μg
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100μg |
10
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$109.90
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Ab182851-1mg
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1mg |
4
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$519.90
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Ab182851-5mg
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5mg |
1
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$1,399.90
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Ab182851-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,239.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Obexelimab (anti-CD19) - Primary antibody, specific to CD19, Human IgG1, INHIBITOR of B-lymphocyte antigen CD19 inhibitor |
|---|---|
| Synonyms | Antibody deficiency due to defect in CD19 antibody | Antibody deficiency due to defect in CD19, included antibody | AW495831 antibody | B lymphocyte antigen CD19 antibody | B lymphocyte surface antigen B4 antibody | B-lymphocyte antigen CD19 antibody | B- |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD19 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of B-lymphocyte antigen CD19 inhibitor |
| Product Description |
Obexelimab (anti-CD19) is a humanized anti-CD19 antibody Fc-engineered for increased affinity to FcγRIIb. Obexelimab (anti-CD19) can be used in research of autoimmune. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.5 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 196.1 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1690307-05-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Obexelimab (anti-CD19) (Ab182851) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 with Obexelimab (anti-CD19) (Ab182851) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
Obexelimab (anti-CD19) (Ab182851) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 (red) with Obexelimab (anti-CD19) (Ab182851) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
Obexelimab (anti-CD19) (Ab182851) - SEC
The purity of Obexelimab (anti-CD19) (Ab182851) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jul 24, 2024 | Ab182851 | |
| Certificate of Analysis | Jul 24, 2024 | Ab182851 | |
| Certificate of Analysis | Jul 24, 2024 | Ab182851 |
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