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Obexelimab (anti-CD19) - Primary antibody, specific to CD19, Human IgG1, INHIBITOR of B-lymphocyte antigen CD19 inhibitor, INHIBITOR of B-lymphocyte antigen CD19 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182851
Grouped product items
SKU Size
Availability
Price Qty
Ab182851-100μg
100μg
10
$109.90
Ab182851-1mg
1mg
4
$519.90
Ab182851-5mg
5mg
1
$1,399.90
Ab182851-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Obexelimab (anti-CD19) - Primary antibody, specific to CD19, Human IgG1, INHIBITOR of B-lymphocyte antigen CD19 inhibitor
Synonyms Antibody deficiency due to defect in CD19 antibody | Antibody deficiency due to defect in CD19, included antibody | AW495831 antibody | B lymphocyte antigen CD19 antibody | B lymphocyte surface antigen B4 antibody | B-lymphocyte antigen CD19 antibody | B-
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD19
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of B-lymphocyte antigen CD19 inhibitor
Product Description

Obexelimab (anti-CD19) is a humanized anti-CD19 antibody Fc-engineered for increased affinity to FcγRIIb. Obexelimab (anti-CD19) can be used in research of autoimmune.
Purity≥95% (SDS-PAGE&SEC)
Endotoxin Level < 0.01EU/μg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.5 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 196.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1690307-05-1

Associated Targets(Human)

CD19 Tclin B-lymphocyte antigen CD19 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Obexelimab (anti-CD19) (Ab182851) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 with Obexelimab (anti-CD19) (Ab182851) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Obexelimab (anti-CD19) (Ab182851) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD19 (red) with Obexelimab (anti-CD19) (Ab182851) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Obexelimab (anti-CD19) (Ab182851) - SEC
The purity of Obexelimab (anti-CD19) (Ab182851) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0708656 Certificate of Analysis Jul 24, 2024 Ab182851
ZJ24F0708655 Certificate of Analysis Jul 24, 2024 Ab182851
ZJ24F0708654 Certificate of Analysis Jul 24, 2024 Ab182851

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