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Therapeutic Antibodies

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  1. Adalimumab (anti-TNF-alpha), INHIBITOR of TNF-alpha inhibitor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  ELANE PRTN3 TNF
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg ; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse, Rhesus monkey    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 331731-18-1        EC Number: 695-701-7
    IUPAC Name:  2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid
    SMILES:  CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O
    InChIKey: BTGNGJJLZOIYID-UHFFFAOYSA-N
    InChI:  InChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)
    Synonyms: dl-N-Acetylhomocysteinethiolactone | ONO5046;LY544349;EI546 | SIVELESTAT [INN] | SIVELESTAT [MART.] | 2,2-Dimethyl-pr...
  2. Avelumab (anti-PD-L1), OTHER of Programmed cell death 1 ligand 1 other
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CD274
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Dog, Human, Mouse, Rabbit, Rat    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 1537032-82-8        Compound CID:  168266339
    IUPAC Name:  4-O-[2-(tert-butylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(cyclohexylmethylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedshow more
    SMILES:  CCS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)CS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)S(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)(C)CS(show more
    InChIKey: YRKYEQYAGDIKGE-UHFFFAOYSA-N
    InChI:  InChI=1S/C20H27NO6S.C19H25NO6S.C18H25NO6S.2C17H23NO6S.C16H21NO6S.C15H19NO6S.C14H17NO6S/c1-26-19(22)12-13-20(23)27-14-18(17-10-6-3-7-11-17)21-28(24,25)show more
    Synonyms: Recombinant Avelumab Antibody | Avelumab | Anti-Human PD-L1, Human Antibody | Anti-PD-L1 | MSB0010718C | Bavencio | B...
  3. Camrelizumab (anti-PD-1), ANTAGONIST of Programmed cell death protein 1 antagonist
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG4SP; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG4SP    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 1798286-48-2
    Synonyms: SHR-1210 | CD279 antigen | CD279 | hPD-1 | PD1 | PD-1 | PD1hPD-l | PDCD1 | programmed cell death 1 | programmed cell ...
  4. Cemiplimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Human    Isotype: Human IgG4    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 1801342-60-8
    Synonyms: hPD-1 | Protein PD-1
  5. Daratumumab (anti-CD38), Antibody of CD38
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CD38
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse, Rhesus monkey    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 945721-28-8
    Synonyms: 2.4.99.20 | 2'-phospho-ADP-ribosyl cyclase | 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase ...
  6. Durvalumab (anti-PD-L1), INHIBITOR of Programmed cell death 1 ligand 1 inhibitor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CD274
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 1428935-60-7
    Synonyms: Durvalumab (anti-PD-L1) | MEDI4736 | Durvalumab | MEDI 4736 | Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (durvalum...
  7. Infliximab (anti-TNF-alpha), INHIBITOR of TNF-alpha inhibitor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 170277-31-3
    Synonyms: Infliximab | Remicade | Remsima | Inflectra | Avakine | CT-P13 | APC1 antibody | APC1 protein antibody | Cachectin an...
  8. Ipilimumab (anti-CTLA-4), Antibody of cytotoxic T-lymphocyte-associated protein 4 (CD152)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CTLA4
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 477202-00-9        EC Number: 274-324-8, 232-352-8, 639-663-1        Compound CID:  167312542
    IUPAC Name:  3-butyl-4-hydroxy-5-methyl-5-(2-methylbuta-1,3-dienyl)thiophen-2-one;4-ethyl-2-methyl-2-(2-methylbuta-1,3-dienyl)-5-methylidenethiophen-3-ol;4-hydroxyshow more
    SMILES:  CCCCC1=C(C(SC1=O)(C)C=C(C)C=C)O.CCCC1=C(C(SC1=O)(C)C=C(C)C=C)O.CCC1=C(C(SC1=C)(C)C=C(C)C=C)O.CC1=CC=C(C=C1)CCCCC2=C(C(SC2=O)(C)C=C(C)C=C)O.CC1=CC=C(C=show more
    InChIKey: QZWDCJBBGBXHMW-UHFFFAOYSA-N
    InChI:  InChI=1S/4C21H26O2S.2C19H22O2S.C14H20O2S.C13H18O2S.C13H18OS/c4*1-5-15(2)14-21(4)19(22)18(20(23)24-21)9-7-6-8-17-12-10-16(3)11-13-17;2*1-5-13(2)12-19(4show more
    Synonyms: MDX-010 | BMS-734016 | Yervoy | Ipilimumab | Ipilimumab (anti-CTLA-4) | Recombinant Ipilimumab Antibody | Ipilimumab ...
  9. Nivolumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG4SP; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG4SP    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 946414-94-4        Compound CID:  168009888
    IUPAC Name:  3-methyl-5-methylsulfonyl-1-(2,2,4-trimethyl-3,4-dihydro-1H-quinolin-8-yl)pent-4-en-1-one;3-methyl-5-methylsulfonyl-1-(2,2,4-trimethyl-1H-quinolin-8-yshow more
    SMILES:  CC1CC(NC2=C1C=CC=C2C(=O)CCC=CS(=O)(=O)C)(C)C.CC1CC(NC2=C1C=CC=C2C(=O)CC(C)C=CS(=O)(=O)C)(C)C.CC1=CC(NC2=C1C=CC=C2C(=O)CCC=CS(=O)(=O)C)(C)C.CC1=CC(NC2=show more
    InChIKey: VSTHRBNUEGPUOM-UHFFFAOYSA-N
    InChI:  InChI=1S/C19H27NO3S.C19H25NO3S.C18H25NO3S.C18H23NO3S/c2*1-13(9-10-24(5,22)23)11-17(21)16-8-6-7-15-14(2)12-19(3,4)20-18(15)16;2*1-13-12-18(2,3)19-17-14show more
    Synonyms: CID 167682467 | hPD-1 | Protein PD-1
  10. Obinutuzumab (anti-CD20), Antibody of CD20 (membrane-spanning 4-domains; subfamily A; member 1)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  MS4A1
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 949142-50-1
    Synonyms: B-lymphocyte surface antigen B1 | Bp35 | Leukocyte surface antigen Leu-16 | Membrane-spanning 4-domains subfamily A m...
  11. Pembrolizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  PDCD1
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG4SP    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 1374853-91-4        EC Number: 807-012-2        Compound CID:  168009853
    IUPAC Name:  1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[2-methylhexadeca-8,10-dienyl(2-methylhexadeca-9,11-dienyl)show more
    SMILES:  CC.CCCCCCCCCCCCC(C)CN(CCCCC=C)CC(CCCCCCCCCCCC)O.CCCCCC=CC=CCCCCCC(C)CN(CCCS)CC(C)CCCCCCC=CC=CCCCC.CCCCN1CCN(CC1)CCC
    InChIKey: AMOIBCKFWIUEKF-UHFFFAOYSA-N
    InChI:  InChI=1S/C37H69NS.C35H71NO.C11H24N2.C2H6/c1-5-7-9-11-13-15-17-19-21-23-25-27-30-36(3)34-38(32-29-33-39)35-37(4)31-28-26-24-22-20-18-16-14-12-10-8-6-2;show more
    Synonyms: 1374853-91-4 | 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[[(8E,10E)-...
  12. Pertuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CYP1A2 ERBB2 ADRB2
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Human, Mouse, Rat    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 380610-27-5        Compound CID:  5484725
    IUPAC Name:  (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
    SMILES:  CC1=C2CCCC2=C(C=C1)OCC(C(C)NC(C)C)O
    InChIKey: VFIDUCMKNJIJTO-BBRMVZONSA-N
    InChI:  InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16-/m0/s1
    Synonyms: 2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, [R-(R*,S*)]- | Q27078025 | (2R,3S)-...
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