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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176090-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab176090-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$289.90
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Ab176090-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$749.90
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Ab176090-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,189.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Ianalumab (anti-TNFRSF13C) - Primary antibody, specific to TNFRSF13C, >95%, high purity, Human IgG1, BINDING AGENT of Tumor necrosis factor receptor superfamily member 13C binding agent |
|---|---|
| Synonyms | B cell activating factor receptor antibody | B-cell-activating factor receptor antibody | BAFF R antibody | BAFF receptor antibody | BAFF-R antibody | BAFFR antibody | BLyS receptor 3 antibody | BlySR3 antibody | BR 3 antibody | BR3 antibody | BROMIX anti |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TNFRSF13C |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Tumor necrosis factor receptor superfamily member 13C binding agent |
| Product Description |
Ianalumab (anti-TNFRSF13C) is a humanized, decarboxylated antibody against BAFF-R. Ianalumab (anti-TNFRSF13C) can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab (anti-TNFRSF13C) exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.8 kDa (Light Chain) & 52.1 kDa (Heavy Chain), under reducing conditions; 182.4 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1929549-92-7 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Ianalumab (anti-TNFRSF13C) (Ab176090) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling TNFRSF13C (red) with Ianalumab (anti-TNFRSF13C) (Ab176090). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Ianalumab (anti-TNFRSF13C) (Ab176090) - SEC
The purity of Ianalumab (anti-TNFRSF13C) (Ab176090) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 26, 2023 | Ab176090 | |
| Certificate of Analysis | Oct 26, 2023 | Ab176090 |