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Ianalumab (anti-TNFRSF13C) - Primary antibody, specific to TNFRSF13C, >95%, high purity, Human IgG1, BINDING AGENT of Tumor necrosis factor receptor superfamily member 13C binding agent, BINDING AGENT of Tumor necrosis factor receptor superfamily member 13C binding agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176090
Grouped product items
SKU Size
Availability
Price Qty
Ab176090-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab176090-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$289.90
Ab176090-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$749.90
Ab176090-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Ianalumab (anti-TNFRSF13C) - Primary antibody, specific to TNFRSF13C, >95%, high purity, Human IgG1, BINDING AGENT of Tumor necrosis factor receptor superfamily member 13C binding agent
Synonyms B cell activating factor receptor antibody | B-cell-activating factor receptor antibody | BAFF R antibody | BAFF receptor antibody | BAFF-R antibody | BAFFR antibody | BLyS receptor 3 antibody | BlySR3 antibody | BR 3 antibody | BR3 antibody | BROMIX anti
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFRSF13C
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of Tumor necrosis factor receptor superfamily member 13C binding agent
Product Description

Ianalumab (anti-TNFRSF13C) is a humanized, decarboxylated antibody against BAFF-R. Ianalumab (anti-TNFRSF13C) can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab (anti-TNFRSF13C) exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.8 kDa (Light Chain) & 52.1 kDa (Heavy Chain), under reducing conditions; 182.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1929549-92-7

Associated Targets(Human)

TNFRSF13C Tbio Tumor necrosis factor receptor superfamily member 13C (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Ianalumab (anti-TNFRSF13C) (Ab176090) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling TNFRSF13C (red) with Ianalumab (anti-TNFRSF13C) (Ab176090). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Ianalumab (anti-TNFRSF13C) (Ab176090) - SEC
The purity of Ianalumab (anti-TNFRSF13C) (Ab176090) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001439 Certificate of Analysis Oct 26, 2023 Ab176090
ZJ23F1001438 Certificate of Analysis Oct 26, 2023 Ab176090

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