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Haptoglobin Mouse mAb - Primary antibody, specific to Haptoglobin, Mouse IgG2b

COA COA
    Application:
  • IHC
  • WB
  • Host species: Mouse
  • Reactive species: Human,Mouse,Rat
  • Isotype: Mouse IgG2b
  • Clone Number: C12
  • Conjugation: Unconjugated
In stock
Item Number
Ab106882
Grouped product items
SKU Size
Availability
 Price Qty
Ab106882-10μl
10μl
10
$69.90
Ab106882-50μl
50μl
4
$199.90
Ab106882-100μl
100μl
2
$359.90
Ab106882-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (C12); Mouse anti Human Haptoglobin Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: HP
Accession#:P00738 (4) Gene ID:3240 (4) Haptoglobin (4) HP (4)

Basic Description

Product Name Haptoglobin Mouse mAb - Primary antibody, specific to Haptoglobin, Mouse IgG2b
Synonyms Zonulin | Binding peptide antibody | BP antibody | Haptoglobin alpha chain antibody | Haptoglobin alpha(1S) beta antibody | Haptoglobin alpha(2FS) beta antibody | Haptoglobin beta chain antibody | Haptoglobin, alpha polypeptide antibody | Haptoglobin, bet
Specifications & Purity Carrier Free, ExactAb™, Validated, High Performance, See COA
Host species Mouse
Specificity Haptoglobin
Immunogen Recombinant Hpt expressed in E.coli (AA 227-378).
Positive Control WB: Mouse liver lysates. IHC: Human liver cancer tissue.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, High Performance, Validated
Product Description

Mouse anti Human Haptoglobin Antibody, Monoclonal (C12), could be used for WB, IHC and so on.
Application:
WB: 0.01-5 µg/mL
IHC: 5-30 µg/mL
Protein Function:
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

Product Properties

Isotype Mouse IgG2b
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified + Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

HP Tbio Haptoglobin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Haptoglobin Mouse mAb (Ab106882) - Western Blot
All lanes: Haptoglobin Mouse mAb (Ab106882) at 1/3000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 38 kDa
Observed band size: 38 kDa
Exposure time: 20.0 s

Haptoglobin Mouse mAb (Ab106882) - IHC
DAB staining on IHC
Samples: Human Liver cancer Tissue
Primary Ab: 30 µg/mL Haptoglobin Mouse mAb (Ab106882)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.

Application

Application Dilution info
IHC

5-30 µg/mL
WB

0.01-5 µg/mL

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0506211 Certificate of Analysis May 28, 2024 Ab106882
ZJ24F0506210 Certificate of Analysis May 28, 2024 Ab106882
ZJ24F0506209 Certificate of Analysis May 28, 2024 Ab106882

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