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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182761-100μg
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100μg |
10
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$109.90
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Ab182761-1mg
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1mg |
4
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$519.90
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Ab182761-5mg
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5mg |
1
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$1,399.90
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Ab182761-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,239.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Gancotamab (anti-HER2) - Primary antibody, specific to ERBB2, Human IgG1, BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent |
|---|---|
| Synonyms | Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C erb B2/neu protein antibody | CD340 antibody | CD340 antigen antibody | Cerb B2/neu protein antibody | CerbB2 antibody | Erb b2 receptor tyr |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | ERBB2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent |
| Product Description |
Gancotamab (anti-HER2) is a HER2-targeted antibody-liposomal Doxorubicin conjugate with antitumor activity. Gancotamab (anti-HER2) encapsulates Doxorubicin to facilitate its delivery to HER2-overexpressing tumor cells. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | lambda |
| SDS-PAGE | 145 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1509928-00-0 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Gancotamab (anti-HER2) (Ab182761) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling HER2 (red) with Gancotamab (anti-HER2) (Ab182761). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Gancotamab (anti-HER2) (Ab182761) - SEC
The purity of Gancotamab (anti-HER2) (Ab182761) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jul 11, 2024 | Ab182761 | |
| Certificate of Analysis | Jul 11, 2024 | Ab182761 | |
| Certificate of Analysis | Jul 11, 2024 | Ab182761 |
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