This is a demo store. No orders will be fulfilled.

Gancotamab (anti-HER2) - Primary antibody, specific to ERBB2, Human IgG1, BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent, BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182761
Grouped product items
SKU Size
Availability
Price Qty
Ab182761-100μg
100μg
10
$109.90
Ab182761-1mg
1mg
4
$519.90
Ab182761-5mg
5mg
1
$1,399.90
Ab182761-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Gancotamab (anti-HER2) - Primary antibody, specific to ERBB2, Human IgG1, BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent
Synonyms Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C erb B2/neu protein antibody | CD340 antibody | CD340 antigen antibody | Cerb B2/neu protein antibody | CerbB2 antibody | Erb b2 receptor tyr
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity ERBB2
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent
Product Description

Gancotamab (anti-HER2) is a HER2-targeted antibody-liposomal Doxorubicin conjugate with antitumor activity. Gancotamab (anti-HER2) encapsulates Doxorubicin to facilitate its delivery to HER2-overexpressing tumor cells.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 145 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1509928-00-0

Associated Targets(Human)

ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERBB2 Tclin Epidermal growth factor receptor and ErbB2 (HER1 and HER2) (186 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERBB2 Tclin Epidermal growth factor receptor (487 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERBB2 Tclin FASN/HER2 (2 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Gancotamab (anti-HER2) (Ab182761) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling HER2 (red) with Gancotamab (anti-HER2) (Ab182761). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Gancotamab (anti-HER2) (Ab182761) - SEC
The purity of Gancotamab (anti-HER2) (Ab182761) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0708115 Certificate of Analysis Jul 11, 2024 Ab182761
ZJ24F0708114 Certificate of Analysis Jul 11, 2024 Ab182761
ZJ24F0708113 Certificate of Analysis Jul 11, 2024 Ab182761

Alternative Products

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.