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Basic Description
| Synonyms | Methanamide | Methanamid | DTXSID8025337 | HSDB 88 | Formimidic acid | Methanimidic acid | Amid kyseliny mravenci | formamide | Formic amide | CCRIS 6240 | formamid | carbamaldehyde | NSC 748 | Amid kyseliny mravenci [Czech] | Formic acid, amide | Methano |
|---|---|
| Specifications & Purity | Moligand™, ACS, ≥99.5% |
| Storage Temp | Argon charged |
| Shipped In | Normal |
| Grade | ACS, Moligand™ |
| Product Description |
The addition of formamide may enhance the specificity and efficiency of amplification of PCR (polymerase chain reaction).It may be used as an ammonia equivalent for the palladium-catalyzed aminocarbonylation of 1-bromo-3-trifluoromethylbenzene to form 3-(trifluoromethyl)benzamide. Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization |
Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
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Superclass
Organic acids and derivatives
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Class
Carboximidic acids and derivatives
- Subclass Carboximidic acids
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Class
Carboximidic acids and derivatives
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Superclass
Organic acids and derivatives
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboximidic acids and derivatives |
| Subclass | Carboximidic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Carboximidic acids |
| Alternative Parents | Organopnictogen compounds Organooxygen compounds Imines Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Carboximidic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Imine - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH (R=H, organic group). |
| External Descriptors | a small molecule |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| Pubchem Sid | 488179541 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179541 |
| IUPAC Name | formamide |
| INCHI | InChI=1S/CH3NO/c2-1-3/h1H,(H2,2,3) |
| InChIKey | ZHNUHDYFZUAESO-UHFFFAOYSA-N |
| Smiles | C(=O)N |
| Isomeric SMILES | C(=O)N |
| WGK Germany | 1 |
| RTECS | LQ0525000 |
| Alternate CAS | 75-12-7,28704-51-0 |
| NSC Number | 748 |
| MeSH Entry Terms | formamide |
| Molecular Weight | 45.04 |
| Beilstein | 505995 |
| Reaxy-Rn | 505995 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=505995&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 L2410081 |
Certificate of Analysis | May 15, 2024 | F120616 |
| E2429361 |
Certificate of Analysis | May 15, 2024 | F120616 |
| E2429369 |
Certificate of Analysis | May 15, 2024 | F120616 |
| B2521010 |
Certificate of Analysis | May 15, 2024 | F120616 |
| C2518034 |
Certificate of Analysis | May 15, 2024 | F120616 |
| E2429370 |
Certificate of Analysis | May 15, 2024 | F120616 |
| E2429371 |
Certificate of Analysis | May 15, 2024 | F120616 |
| D2308979 |
Certificate of Analysis | Apr 14, 2023 | F120616 |
| D2308965 |
Certificate of Analysis | Apr 14, 2023 | F120616 |
| D2308970 |
Certificate of Analysis | Apr 14, 2023 | F120616 |
| D2308982 |
Certificate of Analysis | Apr 14, 2023 | F120616 |
| B2301200 |
Certificate of Analysis | Feb 09, 2023 | F120616 |
| L2201394 |
Certificate of Analysis | Nov 22, 2022 | F120616 |
| L2201384 |
Certificate of Analysis | Nov 22, 2022 | F120616 |
| L2201383 |
Certificate of Analysis | Nov 22, 2022 | F120616 |
| L2201149 |
Certificate of Analysis | Nov 22, 2022 | F120616 |
| F2223041 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
| K2203221 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
| I2222449 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
| F2223038 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
| F2223039 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
| H2217009 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
| F2223040 |
Certificate of Analysis | Jun 08, 2022 | F120616 |
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Chemical and Physical Properties
| Sensitivity | Moisture sensitive. |
|---|---|
| Freezing Point(°C) | 2 °C |
| Refractive Index | 1.447 |
| Flash Point(°F) | 347℉ |
| Flash Point(°C) | 175℃ |
| Boil Point(°C) | 210°C |
| Melt Point(°C) | 2-3°C |
| Molecular Weight | 45.041 g/mol |
| XLogP3 | -0.800 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 45.0215 Da |
| Monoisotopic Mass | 45.0215 Da |
| Topological Polar Surface Area | 43.100 Ų |
| Heavy Atom Count | 3 |
| Formal Charge | 0 |
| Complexity | 12.300 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Alternative Products
Documents & Articles
In Situ Hybridization (ISH) Protocol
Categories: Protocols
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