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DISC-0974 (anti-RGMC) - Primary antibody, specific to HJV, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rat
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab177897
Grouped product items
SKU Size
Availability
Price Qty
Ab177897-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab177897-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab177897-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab177897-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name DISC-0974 (anti-RGMC) - Primary antibody, specific to HJV, >95%, high purity, Human IgG1
Synonyms Hemochromatosis type 2 protein | Hemojuvelin BMP coreceptor | RGM domain family member C
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity HJV
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

DISC-0974 (anti-RGMC) is a humanized monoclonal antibody directed against the bone morphogenetic proteins (BMPs) co-receptor hemojuvelin (HJV) with potential to treat anemia of inflammation and other forms of anemia.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.2 kDa (Light Chain) & 50.9 kDa (Heavy Chain), under reducing conditions; 198.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

HJV Tbio Hemojuvelin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

DISC-0974 (anti-RGMC) (Ab177897) - SEC
The purity of DISC-0974 (anti-RGMC) (Ab177897) is more than 95% verified by HPLC.

DISC-0974 (anti-RGMC) (Ab177897) - Flow Cytometry
pLVX-puro-RGMC-HEK293 cells were stained with DISC-0974 (anti-RGMC) (Ab177897) and negative control protein respectively, washed and then followed by PE and analyzed with the FACS EC50 is 31.00 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0809747 Certificate of Analysis Aug 19, 2024 Ab177897
ZJ24F0809746 Certificate of Analysis Aug 19, 2024 Ab177897

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