Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab094025-10μl
|
10μl |
3
|
$39.90
|
|
|
Ab094025-50μl
|
50μl |
1
|
$129.90
|
|
|
Ab094025-100μl
|
100μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$189.90
|
|
|
Ab094025-1ml
|
1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,599.90
|
|
mAb (YN00466m); Mouse anti Human CD163 Antibody; IHC; Unconjugated
| Product Name | CD163 Mouse mAb - Primary antibody, specific to CD163, Mouse IgG |
|---|---|
| Synonyms | OTTHUMP00000238618 antibody | OTTHUMP00000238619 antibody | OTTHUMP00000238620 antibody | SCARI1 antibody | Scavenger receptor cysteine rich type 1 protein M130 antibody | sCD163 antibody | Soluble CD163 antibody | C163A_HUMAN antibody | CD 163 antibody | |
| Specifications & Purity | Azide Free, Validated, Carrier Free, 1.0 mg/mL |
| Host species | Mouse |
| Specificity | CD163 |
| Immunogen | Peptide |
| Positive Control | IHC: Human liver tissue. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, Validated |
| Product Description |
Mouse anti Human CD163 Antibody, Monoclonal (YN00466m), could be used for IHC and so on. Application
Protein Function Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions. |
| Isotype | Mouse IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein G purified |
| Shape | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CD163 Mouse mAb (Ab094025) - IHC
Immunohistochemistry analysis of paraffin-embedded human liver tissue labelling CD163 with CD163 Mouse mAb (Ab094025) at 1/400 dilution. The section was incubated with Ab094025 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
| Application | Dilution info |
|---|---|
| IHC | 1/200
|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 05, 2024 | Ab094025 | |
| Certificate of Analysis | Jun 05, 2024 | Ab094025 |