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PDGFR

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    SU-5402
      Grade & Purity: 
    • ≥98%
    Cas Number: 215543-92-3
    Formula:  C17H16N2O3        Molecular Weight: 296.32
    IUPAC Name:  3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
    SMILES:  CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
    InChIKey: JNDVEAXZWJIOKB-JYRVWZFOSA-N
    InChI:  InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
    Synonyms: HY-10407G | BCPP000060 | SCHEMBL177917 | SU 5402 | su5402 | SU-5402 | (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)meth...
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  2. , Nerve growth factor receptor Trk-A
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    Regorafenib (BAY 73-4506), Nerve growth factor receptor Trk-A
    Cas Number: 755037-03-7        Compound CID:  11167602
    Formula:  C21H15ClF4N4O3        Molecular Weight: 482.82
    IUPAC Name:  4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
    SMILES:  CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
    InChIKey: FNHKPVJBJVTLMP-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29show more
    Synonyms: CCG-269571 | AB00076187-01 | CHEBI:68647 | 755037-03-7 , Regorafenib | AC-25075 | MFCD16038047 | Regorafenib,BAY 73-4...
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  3. , Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fibroblast growth factor receptor 2;Inhibitor of fibroblast growth factor receptor 3;Inhibitor of fibroblast growth factor receptor 4;Inhibitor of fms related receptor tyrosine kinase 1;Inhibit
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    Nintedanib (BIBF 1120), Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fibroblast growth factor receptor 2;Inhibitor of fibroblast growth factor receptor 3;Inhibitor of fibroblast growth factor receptor 4;Inhibitor of fms related receptor tyrosine kinase 1;Inhibit
    Cas Number: 656247-17-5
    Formula:  C31H33N5O4        Molecular Weight: 539.62
    IUPAC Name:  methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
    SMILES:  CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
    InChIKey: CPMDPSXJELVGJG-UHFFFAOYSA-N
    InChI:  InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-show more
    Synonyms: BIBF 1120 | BIBF-1120 | Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylen...
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  4. Wish List Compare
    SU 16f
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 251356-45-3        Compound CID:  5329150
    Formula:  C24H22N2O3        Molecular Weight: 386.44
    IUPAC Name:  3-[2,4-dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
    SMILES:  CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O
    InChIKey: APYYTEJNOZQZNA-MOSHPQCFSA-N
    InChI:  InChI=1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(show more
    Synonyms: (Z)-3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl-6-phenyl)-1H-pyrrol-3-yl)-propionic acid | VEGFR Tyros...
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    PD-161570
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 192705-80-9        Compound CID:  5328135
    Formula:  C26H35Cl2N7O        Molecular Weight: 532.51
    IUPAC Name:  1-tert-butyl-3-[6-(2,6-dichlorophenyl)-2-[4-(diethylamino)butylamino]pyrido[2,3-d]pyrimidin-7-yl]urea
    SMILES:  CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=C(C=CC=C3Cl)Cl)NC(=O)NC(C)(C)C
    InChIKey: MKVMEJKNLUWFSQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C26H35Cl2N7O/c1-6-35(7-2)14-9-8-13-29-24-30-16-17-15-18(21-19(27)11-10-12-20(21)28)23(31-22(17)32-24)33-25(36)34-26(3,4)5/h10-12,15-16H,6-9,1show more
    Synonyms: DTXSID80416145 | E79105 | HMS3678B11 | 1-tert-Butyl-3-[6-(2,6-dichlorophenyl)-2-[[4- (diethylamino)butyl]amino]pyrido...
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  6. Details
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  7. , Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2
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    Imatinib (STI571), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2
    Cas Number: 152459-95-5
    Formula:  C29H31N7O        Molecular Weight: 493.6
    IUPAC Name:  4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
    SMILES:  CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
    InChIKey: KTUFNOKKBVMGRW-UHFFFAOYSA-N
    InChI:  InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,show more
    Synonyms: 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | CGP-57148 | ...
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  8. Wish List Compare
    Imatinib-d8
      Grade & Purity: 
    • ≥98 atom% D,≥98%
    Cas Number: 1092942-82-9
    Formula:  C29H23D8N7O        Molecular Weight: 501.65
    IUPAC Name:  N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]benzamide
    SMILES:  CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
    InChIKey: KTUFNOKKBVMGRW-AZGHYOHESA-N
    InChI:  InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,show more
    Synonyms: 4-{[4-Methyl(~2~H_8_)piperazin-1-yl]methyl}-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | D...
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  9. Wish List Compare
    Tyrphostin 9
      Grade & Purity: 
    • ≥98%
    Cas Number: 10537-47-0        Compound CID:  5614
    Formula:  C18H22N2O        Molecular Weight: 282.38
    IUPAC Name:  2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile
    SMILES:  CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N
    InChIKey: MZOPWQKISXCCTP-UHFFFAOYSA-N
    InChI:  InChI=1S/C18H22N2O/c1-17(2,3)14-8-12(7-13(10-19)11-20)9-15(16(14)21)18(4,5)6/h7-9,21H,1-6H3
    Synonyms: 2-((3,5-bis(1,1-Dimethylethyl)-4-hydroxyphenyl)methylene)propanedinitrile | Tyrphostin 9AG-17 | Lopac-T-182 | S-15126...
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  10. Wish List Compare
    Tyrphostin AG 1296
    Cas Number: 146535-11-7        Compound CID:  2049
    Formula:  C16H14N2O2        Molecular Weight: 266.29
    IUPAC Name:  6,7-dimethoxy-2-phenylquinoxaline
    SMILES:  COC1=C(C=C2C(=C1)N=CC(=N2)C3=CC=CC=C3)OC
    InChIKey: QNOXYUNHIGOWNY-UHFFFAOYSA-N
    InChI:  InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3
    Synonyms: AG 1296 | AS-62520 | MFCD00270913 | NCGC00163386-01 | Tyrphostin AG 1296 | IDI1_033892 | KBio2_000142 | ag1296 | AG-1...
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  11. Wish List Compare
    Tyrophostin AG1295
      Grade & Purity: 
    • ≥98%
    Cas Number: 71897-07-9        Compound CID:  2048
    Formula:  C16H14N2        Molecular Weight: 234.3
    IUPAC Name:  6,7-dimethyl-2-phenylquinoxaline
    SMILES:  CC1=CC2=NC=C(N=C2C=C1C)C3=CC=CC=C3
    InChIKey: FQNCLVJEQCJWSU-UHFFFAOYSA-N
    InChI:  InChI=1S/C16H14N2/c1-11-8-14-15(9-12(11)2)18-16(10-17-14)13-6-4-3-5-7-13/h3-10H,1-2H3
    Synonyms: 6,7-Dimethyl-2-phenylquinoxaline
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  12. , Fibroblast growth factor receptor inhibitor
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    Nintedanib esylate, Fibroblast growth factor receptor inhibitor
    Cas Number: 656247-18-6
    Formula:  C31H33N5O4・C2H6O3S        Molecular Weight: 649.76
    IUPAC Name:  ethanesulfonic acid;methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
    SMILES:  CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
    InChIKey: ZNMRDZZRAFJOKY-UHFFFAOYSA-N
    InChI:  InChI=1S/C31H33N5O4.C2H6O3S/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(2show more
    Synonyms: methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indo...
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Molecule Type
  1. Small molecule 92 items
  2. Antibody 1 item
Target
  1. PDGFRB 37 items
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  111. SLC47A2 1 item
  112. SLC47A1 1 item
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  125. MAP4K2 1 item
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  128. MAP4K4 1 item
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  131. CA3 1 item
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  134. BMPR2 1 item
  135. BRAF 1 item
  136. BTK 1 item
  137. CA14 1 item
  138. CA7 1 item
  139. CDK6 1 item
  140. SLC25A6 1 item
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  145. APP 1 item
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  147. SUCLA2 1 item
  148. MAPT 1 item
  149. APRT 1 item
  150. GSK3B 1 item
  151. GLRA1 1 item
  152. INSR 1 item
  153. GARS 1 item
  154. NTRK2 1 item
  155. NTRK1 1 item
  156. NTRK3 1 item
  157. MAPK1 1 item
  158. MAP2K1 1 item
  159. OLA1 1 item
  160. MUSK 1 item
  161. MTOR 1 item
Antibody Type
  1. Primary antibody 1 item
Application
  1. Animal Model 1 item
  2. ELISA 1 item
  3. Flow Cytometry 1 item
  4. Functional Assay 1 item
Species reactivity（Reacts with)
  1. Human 1 item
  2. Mouse 1 item
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  1. Human 1 item
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  1. Recombinant 1 item
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  1. Unconjugated 1 item
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  1. Human IgG1 1 item
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  1. Solid 4 items
  2. Liquid 1 item
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  1. ≥98% 46 items
  2. ≥99% 38 items
  3. ≥97% 6 items
  4. ≥98%(HPLC) 4 items
  5. ≥95% 1 item
  6. ≥95%(SDS-PAGE&SEC-HPLC) 1 item
  7. ≥96% 1 item
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  9. ≥98 atom% D,≥98% 1 item
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  1. CHO supernatant 1 item
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  1. Moligand™ 49 items
  2. analytical standard 1 item
  3. Animal Free 1 item
  4. Azide Free 1 item
  5. Carrier Free 1 item
  6. ExactAb™ 1 item
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  9. Validated 1 item
Action Type
  1. INHIBITOR 52 items
  2. ANTAGONIST 1 item
Price
  1. $0.00 - $500.00 108 items
  2. $500.00 - $1,000.00 9 items
  3. $1,000.00 - $1,500.00 5 items
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