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PDGFR

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Items 13-24 of 122

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  1. , Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor
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    Lenvatinib (E7080), Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor
    Cas Number: 417716-92-8
    Formula:  C21H19ClN4O4        Molecular Weight: 426.85
    IUPAC Name:  4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
    SMILES:  COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
    InChIKey: WOSKHXYHFSIKNG-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,show more
    Synonyms: LENVATINIB [MI] | UNII-EE083865G2 | AS-16203 | LEV | NSC800781 | NSC-800781 | DB09078 | AKOS021983298 | LENVATINIB [I...
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  2. , Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor
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    Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor
    Cas Number: 444731-52-6
    Formula:  C21H23N7O2S        Molecular Weight: 437.53
    IUPAC Name:  5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
    SMILES:  CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
    InChIKey: CUIHSIWYWATEQL-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,show more
    Synonyms: 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide | 5-[[4-[(2,3-d...
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  3. , Vascular endothelial growth factor receptor inhibitor
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    Linifanib (ABT-869), Vascular endothelial growth factor receptor inhibitor
    Cas Number: 796967-16-3
    Formula:  C21H18FN5O        Molecular Weight: 375.41
    IUPAC Name:  1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
    SMILES:  CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
    InChIKey: MPVGZUGXCQEXTM-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
    Synonyms: A19393 | D09635 | A-741439 | FT-0696226 | LINIFANIB [INN] | NSC764237 | NSC-764237 | CCG-264767 | J-503186 | Linifani...
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  4. , Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of epidermal growth factor receptor;Inhibitor of HCK proto-oncogene; Src family tyrosine kinase;Inhibitor of kinase insert domain receptor;Inhibitor of mechanistic target of rapamyc
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    PP121, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of epidermal growth factor receptor;Inhibitor of HCK proto-oncogene; Src family tyrosine kinase;Inhibitor of kinase insert domain receptor;Inhibitor of mechanistic target of rapamyc
    Cas Number: 1092788-83-4
    Formula:  C17H17N7        Molecular Weight: 319.36
    IUPAC Name:  1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine
    SMILES:  C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CN=C5C(=C4)C=CN5)N
    InChIKey: NVRXTLZYXZNATH-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H17N7/c18-15-13-14(11-7-10-5-6-19-16(10)20-8-11)23-24(12-3-1-2-4-12)17(13)22-9-21-15/h5-9,12H,1-4H2,(H,19,20)(H2,18,21,22)
    Synonyms: SW218262-2 | PP121 | PP-121 | 1092788-83-4 | BCP02256 | J-504558 | SB16563 | MLS001032035 | NCGC00346619-01 | AC-2846...
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  5. , Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6;Inhibitor of NUAK family kinase 1
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    ON-123300, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6;Inhibitor of NUAK family kinase 1
    Cas Number: 1357470-29-1
    Formula:  C24H27N7O        Molecular Weight: 429.5
    IUPAC Name:  8-cyclopentyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile
    SMILES:  CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4C=C(C(=O)N(C4=N3)C5CCCC5)C#N
    InChIKey: VADOZMZXXRBXNY-UHFFFAOYSA-N
    InChI:  InChI=1S/C24H27N7O/c1-29-10-12-30(13-11-29)20-8-6-19(7-9-20)27-24-26-16-18-14-17(15-25)23(32)31(22(18)28-24)21-4-2-3-5-21/h6-9,14,16,21H,2-5,10-13H2,1show more
    Synonyms: CCG-268995 | SB16989 | 8-cyclopentyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitril...
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  6. , Platelet-derived growth factor receptor alpha inhibitor
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    Amuvatinib (MP-470), Platelet-derived growth factor receptor alpha inhibitor
    Cas Number: 850879-09-3
    Formula:  C23H21N5O3S        Molecular Weight: 447.52
    IUPAC Name:  N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide
    SMILES:  C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
    InChIKey: FOFDIMHVKGYHRU-UHFFFAOYSA-N
    InChI:  InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14Hshow more
    Synonyms: N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide | NSC754349 | NSC-75...
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  7. , Platelet-derived growth factor receptor inhibitor
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    Masitinib (AB1010), Platelet-derived growth factor receptor inhibitor
    Cas Number: 790299-79-5
    Formula:  C28H30N6OS        Molecular Weight: 498.65
    IUPAC Name:  4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
    SMILES:  CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
    InChIKey: WJEOLQLKVOPQFV-UHFFFAOYSA-N
    InChI:  InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19Hshow more
    Synonyms: 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE | Masitinib...
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  8. , Vascular endothelial growth factor receptor inhibitor
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    Pazopanib HCl (GW786034 HCl), Vascular endothelial growth factor receptor inhibitor
      Grade & Purity: 
    • ≥98%
    Cas Number: 635702-64-6
    Formula:  C21H23N7O2S·HCl        Molecular Weight: 473.98
    IUPAC Name:  5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
    SMILES:  CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
    InChIKey: MQHIQUBXFFAOMK-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(show more
    Synonyms: GW786034 HCl | 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydroch...
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  9. , Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of cyclin dependent kinase 19;Inhibitor of cyclin dependent kinase 8;Inhibitor of receptor interacting serine/threonine kinase 1;Inhibitor of receptor interacting serine/threonine k
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    Ponatinib (AP24534), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of cyclin dependent kinase 19;Inhibitor of cyclin dependent kinase 8;Inhibitor of receptor interacting serine/threonine kinase 1;Inhibitor of receptor interacting serine/threonine k
    Cas Number: 943319-70-8
    Formula:  C29H27F3N6O        Molecular Weight: 532.57
    IUPAC Name:  3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
    SMILES:  CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
    InChIKey: PHXJVRSECIGDHY-UHFFFAOYSA-N
    InChI:  InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,show more
    Synonyms: 4340891KFS | BDBM50322535 | Dithioglycerol (VAN) | 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-{4-[(4-meth...
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    DMPQ dihydrochloride
      Grade & Purity: 
    • ≥99%
    Cas Number: 1123491-15-5        Compound CID:  45073427
    Formula:  C16H14N2O2.2HCl        Molecular Weight: 339.22
    IUPAC Name:  5,7-dimethoxy-3-pyridin-4-ylquinoline;dihydrochloride
    SMILES:  COC1=CC2=C(C=C(C=N2)C3=CC=NC=C3)C(=C1)OC.Cl.Cl
    InChIKey: YBBAOKYVJCNJIV-UHFFFAOYSA-N
    InChI:  InChI=1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
    Synonyms: 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride | 5,7-Dimethoxy-3-(4-pyridinyl)quinolinedihydrochloride
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  11. , Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor alpha;Inhibitor of platelet derived growth
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    AC 710, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor alpha;Inhibitor of platelet derived growth
    Cas Number: 1351522-04-7
    Formula:  C31H42N6O4        Molecular Weight: 562.7
    IUPAC Name:  N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide
    SMILES:  CCN1C(CC(CC1(C)C)OC2=CN=C(C=C2)C(=O)NC3=CC=C(C=C3)NC(=O)NC4=NOC(=C4)C(C)(C)C)(C)C
    InChIKey: JVCWPUFNLFSKFS-UHFFFAOYSA-N
    InChI:  InChI=1S/C31H42N6O4/c1-9-37-30(5,6)17-23(18-31(37,7)8)40-22-14-15-24(32-19-22)27(38)33-20-10-12-21(13-11-20)34-28(39)35-26-16-25(41-36-26)29(2,3)4/h10show more
    Synonyms: N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperid...
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    AG-370
      Grade & Purity: 
    • ≥99%
    Cas Number: 134036-53-6
    Formula:  C15H9N5        Molecular Weight: 259.3
    IUPAC Name:  (3Z)-2-amino-4-(1H-indol-5-yl)buta-1,3-diene-1,1,3-tricarbonitrile
    SMILES:  C1=CC2=C(C=CN2)C=C1C=C(C#N)C(=C(C#N)C#N)N
    InChIKey: CMMDWEJTQUTCKG-WUXMJOGZSA-N
    InChI:  InChI=1S/C15H9N5/c16-7-12(15(19)13(8-17)9-18)6-10-1-2-14-11(5-10)3-4-20-14/h1-6,20H,19H2/b12-6+
    Synonyms: (3Z)-2-Amino-4-(1H-indol-5-yl)buta-1,3-diene-1,1,3-tricarbonitrile
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  1. Small molecule 92 items
  2. Antibody 1 item
Target
  1. PDGFRB 37 items
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  5. CSF1R 23 items
  6. FLT4 17 items
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  48. FGFR4 2 items
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  50. CSNK1D 2 items
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  52. MERTK 2 items
  53. SLK 2 items
  54. PLK4 2 items
  55. PHKG1 2 items
  56. PHKG2 2 items
  57. RIPK2 2 items
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  80. NUAK1 2 items
  81. MAP2K5 2 items
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  84. CSK 1 item
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  86. EPHA2 1 item
  87. EPHA5 1 item
  88. DDX1 1 item
  89. EPHA1 1 item
  90. PTK2 1 item
  91. CA5A 1 item
  92. CDK4 1 item
  93. DDX3X 1 item
  94. CYP2C9 1 item
  95. RAF1 1 item
  96. PRKDC 1 item
  97. SRPRA 1 item
  98. SRMS 1 item
  99. ROS1 1 item
  100. STK26 1 item
  101. STK3 1 item
  102. STK35 1 item
  103. EPHX2 1 item
  104. IKBKE 1 item
  105. ABCB1 1 item
  106. HIPK4 1 item
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  108. MELK 1 item
  109. SIK2 1 item
  110. SMO 1 item
  111. SLC47A2 1 item
  112. SLC47A1 1 item
  113. SLC6A4 1 item
  114. SNCA 1 item
  115. FARSB 1 item
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  122. PIK3CD 1 item
  123. RIPK3 1 item
  124. RIPK1 1 item
  125. MAP4K2 1 item
  126. NEK2 1 item
  127. MARK4 1 item
  128. MAP4K4 1 item
  129. CA6 1 item
  130. CA1 1 item
  131. CA3 1 item
  132. CA2 1 item
  133. CA12 1 item
  134. BMPR2 1 item
  135. BRAF 1 item
  136. BTK 1 item
  137. CA14 1 item
  138. CA7 1 item
  139. CDK6 1 item
  140. SLC25A6 1 item
  141. ABCG2 1 item
  142. TNK2 1 item
  143. ACOX1 1 item
  144. ACSL5 1 item
  145. APP 1 item
  146. CHEK1 1 item
  147. SUCLA2 1 item
  148. MAPT 1 item
  149. APRT 1 item
  150. GSK3B 1 item
  151. GLRA1 1 item
  152. INSR 1 item
  153. GARS 1 item
  154. NTRK2 1 item
  155. NTRK1 1 item
  156. NTRK3 1 item
  157. MAPK1 1 item
  158. MAP2K1 1 item
  159. OLA1 1 item
  160. MUSK 1 item
  161. MTOR 1 item
Antibody Type
  1. Primary antibody 1 item
Application
  1. Animal Model 1 item
  2. ELISA 1 item
  3. Flow Cytometry 1 item
  4. Functional Assay 1 item
Species reactivity（Reacts with)
  1. Human 1 item
  2. Mouse 1 item
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  1. Human 1 item
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  1. Recombinant 1 item
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  1. Unconjugated 1 item
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  1. Human IgG1 1 item
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  1. Solid 4 items
  2. Liquid 1 item
Purity
  1. ≥98% 46 items
  2. ≥99% 38 items
  3. ≥97% 6 items
  4. ≥98%(HPLC) 4 items
  5. ≥95% 1 item
  6. ≥95%(SDS-PAGE&SEC-HPLC) 1 item
  7. ≥96% 1 item
  8. ≥97%(HPLC) 1 item
  9. ≥98 atom% D,≥98% 1 item
Source
  1. CHO supernatant 1 item
Grade
  1. Moligand™ 49 items
  2. analytical standard 1 item
  3. Animal Free 1 item
  4. Azide Free 1 item
  5. Carrier Free 1 item
  6. ExactAb™ 1 item
  7. Low Endotoxin 1 item
  8. Recombinant 1 item
  9. Validated 1 item
Action Type
  1. INHIBITOR 52 items
  2. ANTAGONIST 1 item
Price
  1. $0.00 - $500.00 108 items
  2. $500.00 - $1,000.00 9 items
  3. $1,000.00 - $1,500.00 5 items
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