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Protein Degrader Building Blocks

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3 Items

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  1. , Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Channel blocker of CaCC;Gating inhibitor of K ir3.2;Gating inhibitor of K v3.1;Inhibitor of Plasma membrane monoamine transporter;In
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    Fluoxetine, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Channel blocker of CaCC;Gating inhibitor of K ir3.2;Gating inhibitor of K v3.1;Inhibitor of Plasma membrane monoamine transporter;In
    Cas Number: 54910-89-3
    Formula:  C17H18F3NO        Molecular Weight: 309.33
    IUPAC Name:  N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
    SMILES:  CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
    InChIKey: RTHCYVBBDHJXIQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
    Synonyms: (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine | N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propy...
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  2. , Agonist of succinate receptor
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    (1R,2S)‐rel-cyclopropane‐1,2‐dicarboxylic acid, Agonist of succinate receptor
    Cas Number: 696-74-2        EC Number: 633-227-4
    Formula:  C5H6O4        Molecular Weight: 130.10
    IUPAC Name:  (1S,2R)-cyclopropane-1,2-dicarboxylic acid
    SMILES:  C1C(C1C(=O)O)C(=O)O
    InChIKey: RLWFMZKPPHHHCB-WSOKHJQSSA-N
    InChI:  InChI=1S/C5H6O4/c6-4(7)2-1-3(2)5(8)9/h2-3H,1H2,(H,6,7)(H,8,9)/t2-,3+
    Synonyms: 696-74-2|(1R,2S)-rel-Cyclopropane-1,2-dicarboxylic acid|(1r,2s)-cyclopropane-1,2-dicarboxylic acid|cis-1,2-cyclopropa...
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  3. , Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Channel blocker of CaCC;Gating inhibitor of K ir3.2;Gating inhibitor of K v3.1;Inhibitor of Plasma membrane monoamine transporter;In
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    Fluoxetine, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Channel blocker of CaCC;Gating inhibitor of K ir3.2;Gating inhibitor of K v3.1;Inhibitor of Plasma membrane monoamine transporter;In
    Cas Number: 54910-89-3
    Formula:  C17H18F3NO        Molecular Weight: 309.33
    IUPAC Name:  N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
    SMILES:  CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
    InChIKey: RTHCYVBBDHJXIQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
    Synonyms: N-methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine | Fluoxin
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    KCNJ6
  2. Target
    SUCNR1
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  1. Small molecule 2 items
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  1. CA2 10 items
  2. KCNH2 9 items
  3. CA12 8 items
  4. CA9 8 items
  5. HTR2C 5 items
  6. SLC6A4 4 items
  7. PARP1 4 items
  8. CA1 4 items
  9. HTR2A 4 items
  10. ACHE 4 items
  11. DAO 4 items
  12. CYP1A2 3 items
  13. CYP2D6 3 items
  14. CES1 3 items
  15. PNMT 3 items
  16. CYP11B2 3 items
  17. CYP11B1 3 items
  18. CHRM4 3 items
  19. CHRM2 3 items
  20. HTR2B 3 items
  21. NOTUM 3 items
  22. IDO1 3 items
  23. CYP2A6 2 items
  24. DRD2 2 items
  25. CES2 2 items
  26. BRD4 2 items
  27. KCNJ6 2 items
  28. KCNC1 2 items
  29. S1PR1 2 items
  30. SLC29A4 2 items
  31. SLC6A2 2 items
  32. SLC6A3 2 items
  33. SCN5A 2 items
  34. SCN9A 2 items
  35. SIGMAR1 2 items
  36. KMO 2 items
  37. MMP9 2 items
  38. MCOLN1 2 items
  39. MMP2 2 items
  40. BRDT 2 items
  41. BRD3 2 items
  42. BRD2 2 items
  43. CA7 2 items
  44. CYP19A1 2 items
  45. BACE1 2 items
  46. CHRM5 2 items
  47. CHRM3 2 items
  48. CHRM1 2 items
  49. ADRB1 2 items
  50. GFER 2 items
  51. MAOB 2 items
  52. ANO1 2 items
  53. HTR6 2 items
  54. CYP1B1 1 item
  55. GJA10 1 item
  56. GJA8 1 item
  57. GJA4 1 item
  58. GJB6 1 item
  59. GJB1 1 item
  60. GJB3 1 item
  61. GJD4 1 item
  62. GJE1 1 item
  63. GJB4 1 item
  64. GJA1 1 item
  65. GJA5 1 item
  66. GJA9 1 item
  67. GJB7 1 item
  68. GJB2 1 item
  69. GJD3 1 item
  70. GJB5 1 item
  71. CYP2C19 1 item
  72. GJD2 1 item
  73. CDK1 1 item
  74. GJA3 1 item
  75. GJC1 1 item
  76. GJC2 1 item
  77. GJC3 1 item
  78. EGLN1 1 item
  79. GABRA1 1 item
  80. NR3C1 1 item
  81. GABRA3 1 item
  82. GABRA5 1 item
  83. DDR2 1 item
  84. F10 1 item
  85. EGFR 1 item
  86. CCR2 1 item
  87. CCKAR 1 item
  88. DCLK3 1 item
  89. HSD11B2 1 item
  90. HSD11B1 1 item
  91. GABRA2 1 item
  92. CYP2C9 1 item
  93. CDK2 1 item
  94. CRHR1 1 item
  95. DDR1 1 item
  96. PSMB5 1 item
  97. HCRTR1 1 item
  98. SCN2A 1 item
  99. SLC5A8 1 item
  100. S1PR5 1 item
  101. S1PR4 1 item
  102. RNASEH1 1 item
  103. SLC15A1 1 item
  104. SUCNR1 1 item
  105. TYK2 1 item
  106. TYMS 1 item
  107. HRH4 1 item
  108. HSP90AA1 1 item
  109. EPHX2 1 item
  110. HRH3 1 item
  111. HRH2 1 item
  112. HIF1A 1 item
  113. HCAR2 1 item
  114. FAAH 1 item
  115. EPHX1 1 item
  116. HRH1 1 item
  117. JAK3 1 item
  118. TRPV1 1 item
  119. TPH1 1 item
  120. SLC9A1 1 item
  121. SLC5A2 1 item
  122. SCN10A 1 item
  123. SCN3A 1 item
  124. SLC5A1 1 item
  125. SCN4A 1 item
  126. SCN1A 1 item
  127. SCN8A 1 item
  128. SYNJ2 1 item
  129. TRIM24 1 item
  130. TOP1 1 item
  131. THRA 1 item
  132. TTK 1 item
  133. PKN1 1 item
  134. PLK1 1 item
  135. PTGS1 1 item
  136. RARB 1 item
  137. RARA 1 item
  138. PTGS2 1 item
  139. PANX2 1 item
  140. KDM4B 1 item
  141. KDM4C 1 item
  142. KDM6B 1 item
  143. KIF11 1 item
  144. MIF 1 item
  145. MCOLN2 1 item
  146. MCOLN3 1 item
  147. LOXL2 1 item
  148. ALOX5 1 item
  149. LOXL3 1 item
  150. LIPG 1 item
  151. OGG1 1 item
  152. JAK1 1 item
  153. CTSB 1 item
  154. CACNA1I 1 item
  155. CACNA1C 1 item
  156. CTSD 1 item
  157. CA4 1 item
  158. BTK 1 item
  159. CA14 1 item
  160. CYP1A1 1 item
  161. SLC18A2 1 item
  162. ADRB2 1 item
  163. HTR4 1 item
  164. ACKR3 1 item
  165. SCD 1 item
  166. AKR1C2 1 item
  167. ADRA2A 1 item
  168. AKR1C3 1 item
  169. ALDH3A1 1 item
  170. ADRA1D 1 item
  171. ALDH1A1 1 item
  172. ALDH2 1 item
  173. APP 1 item
  174. TRIM33 1 item
  175. TAS2R9 1 item
  176. UPP1 1 item
  177. THRB 1 item
  178. F2 1 item
  179. ASIC3 1 item
  180. CLK4 1 item
  181. EDNRA 1 item
  182. GRM5 1 item
  183. GRM8 1 item
  184. FOLH1 1 item
  185. IMPDH2 1 item
  186. SHMT2 1 item
  187. PANX3 1 item
  188. PANX1 1 item
  189. HCRTR2 1 item
  190. P2RX7 1 item
  191. GRIN1 1 item
  192. NOS2 1 item
  193. NPY5R 1 item
  194. GRIN2B 1 item
  195. JAK2 1 item
  196. KDM3A 1 item
  197. KDM4E 1 item
  198. MAP2K1 1 item
  199. NAALAD2 1 item
  200. NOS1 1 item
  201. PNP 1 item
  202. NOS3 1 item
Purity
  1. ≥95% 1 item
  2. ≥97% 1 item
  3. ≥99% 1 item
Action Type
  1. ANTAGONIST 2 items
  2. CHANNEL BLOCKER 2 items
  3. GATING INHIBITOR 2 items
  4. INHIBITOR 2 items
  5. AGONIST 1 item
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