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Protein Degrader Building Blocks

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  1. Fluoxetine, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Channel blocker of CaCC;Gating inhibitor of K ir3.2;Gating inhibitor of K v3.1;Inhibitor of Plasma membrane monoamine transporter;In
    Cas Number: 54910-89-3
    Formula:  C17H18F3NO        Molecular Weight: 309.33
    IUPAC Name:  N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
    SMILES:  CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
    InChIKey: RTHCYVBBDHJXIQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
    Synonyms: (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine | N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propy...
  2. 4,6-Dichloro-1h-indole-2,3-dione
      Grade & Purity: 
    • ≥95%
    Cas Number: 18711-15-4
    Formula:  C8H3Cl2NO2        Molecular Weight: 216
    IUPAC Name:  4,6-dichloro-1H-indole-2,3-dione
    SMILES:  C1=C(C=C(C2=C1NC(=O)C2=O)Cl)Cl
    InChIKey: CGCVHJCZBIYRQC-UHFFFAOYSA-N
    InChI:  InChI=1S/C8H3Cl2NO2/c9-3-1-4(10)6-5(2-3)11-8(13)7(6)12/h1-2H,(H,11,12,13)
    Synonyms: 4,6-Dichloroisatin|18711-15-4|4,6-Dichloro-1H-indole-2,3-dione|4,6-DICHLOROINDOLINE-2,3-DIONE|4,6-dichloro-2,3-dihydr...
  3. 1-(3,4-DIMETHYL-PHENYL)-2-PHENYL-ETHANE-1,2-DIONE
    Cas Number: 59411-15-3
    Formula:  C16H14O2        Molecular Weight: 238.289
    IUPAC Name:  1-(3,4-dimethylphenyl)-2-phenylethane-1,2-dione
    SMILES:  CC1=C(C=C(C=C1)C(=O)C(=O)C2=CC=CC=C2)C
    InChIKey: UJARQLWFLLIFBN-UHFFFAOYSA-N
    InChI:  InChI=1S/C16H14O2/c1-11-8-9-14(10-12(11)2)16(18)15(17)13-6-4-3-5-7-13/h3-10H,1-2H3
    Synonyms: 1-(3,4-dimethylphenyl)-2-phenylethane-1,2-dione|59411-15-3|Benzil-based compound, 19|1-(3,4-Dimethyl-phenyl)-2-phenyl...
  4. 1-(4-CHLOROBENZYL)ISATIN
    Cas Number: 26960-66-7
    Formula:  C15H10ClNO2        Molecular Weight: 271.705
    IUPAC Name:  1-[(4-chlorophenyl)methyl]indole-2,3-dione
    SMILES:  C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC=C(C=C3)Cl
    InChIKey: VEBLIIOSJXGVAW-UHFFFAOYSA-N
    InChI:  InChI=1S/C15H10ClNO2/c16-11-7-5-10(6-8-11)9-17-13-4-2-1-3-12(13)14(18)15(17)19/h1-8H,9H2
    Synonyms: 1-(4-Chlorobenzyl)-1H-indole-2,3-dione|26960-66-7|1-(4-Chlorobenzyl)indoline-2,3-dione|1-(4-chloro-benzyl)-1h-indole-...
  5. Fluoxetine, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 6 receptor;Channel blocker of CaCC;Gating inhibitor of K ir3.2;Gating inhibitor of K v3.1;Inhibitor of Plasma membrane monoamine transporter;In
    Cas Number: 54910-89-3
    Formula:  C17H18F3NO        Molecular Weight: 309.33
    IUPAC Name:  N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
    SMILES:  CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
    InChIKey: RTHCYVBBDHJXIQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
    Synonyms: N-methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine | Fluoxin
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