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Protein Degrader Building Blocks

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  1. LSN2463359, Allosteric modulator of mGlu 5 receptor
    Cas Number: 1401031-52-4
    Formula:  C16H15N3O        Molecular Weight: 265.31
    IUPAC Name:  N-propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide
    SMILES:  CC(C)NC(=O)C1=NC=C(C=C1)C#CC2=CC=NC=C2
    InChIKey: STAFRSGTRKNXHF-UHFFFAOYSA-N
    InChI:  InChI=1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20)
    Synonyms: BGC03152 | GTPL6394 | 2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]- | N-Isopropyl-5-(pyridin-4...
  2. Carbenoxolone, 11-beta-hydroxysteroid dehydrogenase inhibitor
    Cas Number: 5697-56-3
    Formula:  C34H50O7        Molecular Weight: 570.76
    IUPAC Name:  (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-show more
    SMILES:  CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(=O)O)OC(=O)CCC(=O)O
    InChIKey: OBZHEBDUNPOCJG-WBXJDKIVSA-N
    InChI:  InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h1show more
    Synonyms: Olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo-, (3ß,20ß)- | Olean-12-en-30-oic acid, 3ß-hydroxy-11-oxo-,...
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