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Vofatamab (anti-FGFR3) - Primary antibody, specific to FGFR3, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab177923
Grouped product items
SKU Size
Availability
Price Qty
Ab177923-100μg
100μg
10
$79.90
Ab177923-1mg
1mg
4
$389.90
Ab177923-5mg
5mg
1
$979.90
Ab177923-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,569.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Vofatamab (anti-FGFR3) - Primary antibody, specific to FGFR3, >95%, high purity, Human IgG1
Synonyms ACH antibody | CD 333 antibody | CD333 antibody | CD333 antigen antibody | CEK 2 antibody | CEK2 antibody | FGFR 3 antibody | FGFR-3 antibody | FGFR3 antibody | FGFR3_HUMAN antibody | Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarf
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity FGFR3
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Vofatamab (anti-FGFR3) is an anti-FGFR3 monoclonal antibody (mAb). Vofatamab (anti-FGFR3) blocks activation of both the wildtype and genetically activated receptor. Vofatamab (anti-FGFR3) can be used in the research of metastatic urothelial carcinoma (mUC).

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 150kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1312305-12-6

Associated Targets(Human)

FGFR3 Tclin Fibroblast growth factor receptor 3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
FGFR3 Tclin Fibroblast growth factor receptor 3 (7811 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FGFR3 Tclin Fibroblast growth factor receptor (331 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Vofatamab (anti-FGFR3) (Ab177923) - ELISA
Immobilized Human FGFR3c-Chis at 2.0 μg/mL can bind Vofatamab (anti-FGFR3) (Ab177923) with the EC₅₀ of 19.06 ng/mL.

Vofatamab (anti-FGFR3) (Ab177923) - SEC
The purity of Vofatamab (anti-FGFR3) (Ab177923) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404040 Certificate of Analysis Apr 02, 2024 Ab177923
ZJ24F0404041 Certificate of Analysis Apr 02, 2024 Ab177923
ZJ24F0404039 Certificate of Analysis Apr 02, 2024 Ab177923

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