Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab177923-100μg
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100μg |
10
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$79.90
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Ab177923-1mg
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1mg |
4
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$389.90
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Ab177923-5mg
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5mg |
1
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$979.90
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Ab177923-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,569.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Vofatamab (anti-FGFR3) - Primary antibody, specific to FGFR3, >95%, high purity, Human IgG1 |
|---|---|
| Synonyms | ACH antibody | CD 333 antibody | CD333 antibody | CD333 antigen antibody | CEK 2 antibody | CEK2 antibody | FGFR 3 antibody | FGFR-3 antibody | FGFR3 antibody | FGFR3_HUMAN antibody | Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarf |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | FGFR3 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Vofatamab (anti-FGFR3) is an anti-FGFR3 monoclonal antibody (mAb). Vofatamab (anti-FGFR3) blocks activation of both the wildtype and genetically activated receptor. Vofatamab (anti-FGFR3) can be used in the research of metastatic urothelial carcinoma (mUC). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1312305-12-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Vofatamab (anti-FGFR3) (Ab177923) - ELISA
Immobilized Human FGFR3c-Chis at 2.0 μg/mL can bind Vofatamab (anti-FGFR3) (Ab177923) with the EC₅₀ of 19.06 ng/mL.
Vofatamab (anti-FGFR3) (Ab177923) - SEC
The purity of Vofatamab (anti-FGFR3) (Ab177923) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 02, 2024 | Ab177923 | |
| Certificate of Analysis | Apr 02, 2024 | Ab177923 | |
| Certificate of Analysis | Apr 02, 2024 | Ab177923 |
Starting at $129.90