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Tusamitamab (anti-CEACAM5) - Primary antibody, specific to CEACAM5, >95%, high purity, Human IgG1

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176222
Grouped product items
SKU Size
Availability
 Price Qty
Ab176222-100μg
100μg
10
$49.90
Ab176222-1mg
1mg
4
$239.90
Ab176222-5mg
5mg
1
$619.90
Ab176222-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$979.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CEACAM5
Accession#:P06731 (12) CD66e (12) CEA (12) CEACAM5 (13) Gene ID:1048 (13)

Basic Description

Product Name Tusamitamab (anti-CEACAM5) - Primary antibody, specific to CEACAM5, >95%, high purity, Human IgG1
Synonyms Carcinoembryonic antigen antibody | Carcinoembryonic antigen-related cell adhesion molecule 5 antibody | CD66e antibody | CEA antibody | Ceacam5 antibody | CEAM5_HUMAN antibody | DKFZp781M2392 antibody | Meconium antigen 100 antibody | OTTHUMP00000199032
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CEACAM5
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Tusamitamab (anti-CEACAM5) is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab (anti-CEACAM5) can be used to synthesize Tusamitamab ravtansine, which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab (anti-CEACAM5) and DM4 (a potent maytansine derivative).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.6 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 172.9 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2349294-95-5

Associated Targets(Human)

CEACAM5 Tbio Carcinoembryonic antigen-related cell adhesion molecule 5 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tusamitamab (anti-CEACAM5) (Ab176222) - ELISA
Immobilized hu-CEACAM5-His at 2 μg/mL can bind Tusamitamab (anti-CEACAM5) (Ab176222) with the EC₅₀ of 4.02 ng/mL.

Tusamitamab (anti-CEACAM5) (Ab176222) - SEC
The purity of Tusamitamab (anti-CEACAM5) (Ab176222) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303027 Certificate of Analysis Mar 08, 2024 Ab176222
ZJ24F0303026 Certificate of Analysis Mar 08, 2024 Ab176222
ZJ24F0303025 Certificate of Analysis Mar 08, 2024 Ab176222

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