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Ragifilimab (anti-TNFRSF18) - Primary antibody, specific to TNFRSF18, >95%, high purity, Human IgG1, AGONIST of Tumor necrosis factor receptor superfamily member 18 agonist, AGONIST of Tumor necrosis factor receptor superfamily member 18 agonist

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176088
Grouped product items
SKU Size
Availability
Price Qty
Ab176088-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
Ab176088-1mg
1mg
5
$169.90
Ab176088-5mg
5mg
1
$399.90
Ab176088-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$659.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Ragifilimab (anti-TNFRSF18) - Primary antibody, specific to TNFRSF18, >95%, high purity, Human IgG1, AGONIST of Tumor necrosis factor receptor superfamily member 18 agonist
Synonyms Activation inducible TNFR family receptor antibody | Activation-inducible TNFR family receptor antibody | AITR antibody | CD357 antibody | GITR antibody | GITR D antibody | GITR-D antibody | GITRD antibody | Glucocorticoid induced TNFR related protein ant
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFRSF18
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type AGONIST
Mechanism of action AGONIST of Tumor necrosis factor receptor superfamily member 18 agonist
Product Description

Ragifilimab (anti-TNFRSF18) is an agonist monoclonal antibody targeting the glucocorticoid-induced TNFR-related protein (GITR). Ragifilimab (anti-TNFRSF18) can be used for advanced or metastatic solid tumors research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.8 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 176.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2207590-51-8

Associated Targets(Human)

TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Ragifilimab (anti-TNFRSF18) (Ab176088) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling TNFRSF18 with Ragifilimab (anti-TNFRSF18) (Ab176088) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Ragifilimab (anti-TNFRSF18) (Ab176088) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling TNFRSF18 (red) with Ragifilimab (anti-TNFRSF18) (Ab176088) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Ragifilimab (anti-TNFRSF18) (Ab176088) - SEC
The purity of Ragifilimab (anti-TNFRSF18) (Ab176088) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101574 Certificate of Analysis Nov 08, 2023 Ab176088
ZJ23F1101557 Certificate of Analysis Nov 08, 2023 Ab176088

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