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Emactuzumab (anti-CSF1R) - Primary antibody, specific to CSF1R, >95%, high purity, Human IgG1, Antibody of colony stimulating factor 1 receptor, Antibody of colony stimulating factor 1 receptor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175525
Grouped product items
SKU Size
Availability
Price Qty
Ab175525-100μg
100μg
10
$59.90
Ab175525-1mg
1mg
4
$259.90
Ab175525-5mg
5mg
1
$749.90
Ab175525-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Emactuzumab (anti-CSF1R) - Primary antibody, specific to CSF1R, >95%, high purity, Human IgG1, Antibody of colony stimulating factor 1 receptor
Synonyms C FMS antibody | CD 115 antibody | CD115 antibody | CD115 antigen antibody | CFMS antibody | Colony stimulating factor 1 receptor antibody | Colony stimulating factor I receptor antibody | CSF 1 R antibody | CSF 1R antibody | CSF-1 receptor antibody | CSF
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CSF1R
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of colony stimulating factor 1 receptor
Product Description

Emactuzumab (anti-CSF1R) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab (anti-CSF1R) has high affinity for CSF-1R with Ki value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab (anti-CSF1R) can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT).

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.5 kDa (Light Chain) & 51.1kDa (Heavy Chain), under reducing conditions; 200.2 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1448221-67-7

Associated Targets(Human)

CSF1R Tclin Macrophage colony-stimulating factor 1 receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Emactuzumab (anti-CSF1R) (Ab175525) - ELISA
Immobilized Hu-CSF1R-his at 2 μg/mL can bind Emactuzumab (anti-CSF1R) (Ab175525) with the EC₅₀ of 12.40 ng/mL.


Emactuzumab (anti-CSF1R) (Ab175525) - SEC
The purity of Emactuzumab (anti-CSF1R) (Ab175525) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303909 Certificate of Analysis Mar 29, 2024 Ab175525
ZJ24F0303908 Certificate of Analysis Mar 29, 2024 Ab175525
ZJ24F0303907 Certificate of Analysis Mar 29, 2024 Ab175525

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