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CD278/ICOS Armenian Hamster mAb - Primary antibody, specific to ICOS, Armenian Hamster IgG

    Application:
  • Flow Cytometry
  • Host species: Armenian hamster
  • Reactive species: Human,Mouse,Rat
  • Isotype: Armenian Hamster IgG
  • Clone Number: C398.4A
  • Conjugation: Unconjugated
In stock
Item Number
Ab109269
Grouped product items
SKU Size
Availability
Price Qty
Ab109269-10μg
10μg
10
$26.90
Ab109269-50μg
50μg
4
$69.90
Ab109269-100μg
100μg
2
$119.90
Ab109269-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$529.90

mAb (C398.4A); Armenian Hamster anti Human CD278/ICOS Antibody; Flow; Unconjugated

Basic Description

Product Name CD278/ICOS Armenian Hamster mAb - Primary antibody, specific to ICOS, Armenian Hamster IgG
Synonyms Activation-inducible lymphocyte immunomediatory molecule | AILIM | AILIMCD278 | CD278 antigen | CD278 | CRP-1 | CVID1 | ICOS | inducible costimulator | inducible T-cell costimulator | inducible T-cell co-stimulator | MGC39850 | Activation inducible lympho
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, See COA
Host species Armenian hamster
Specificity ICOS
Immunogen Mouse T cell clone D10.G4.1
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Armenian Hamster anti Human CD278/ICOS Antibody, Monoclonal (C398.4A), could be used for Flow and so on.
Application:
Flow: 1.0 μg/100w cells
Protein Function
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

Product Properties

Isotype Armenian Hamster IgG
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

ICOS Tbio Inducible T-cell costimulator (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD278/ICOS Armenian Hamster mAb (Ab109269) - Flow Cytometry
Flow Cytometry analysis of MOLT-4 cells labelling CD278/ICOS (red) with CD278/ICOS Armenian Hamster mAb (Ab109269) conjugated with biotin at 5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow Cytometry

1μg/100w cells

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505797 Certificate of Analysis May 20, 2024 Ab109269
ZJ24F0505798 Certificate of Analysis May 20, 2024 Ab109269
ZJ24F0505799 Certificate of Analysis May 20, 2024 Ab109269

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